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Elucidating the potential carcinogenic molecular mechanisms of parabens in head and neck squamous cell carcinoma through network toxicology and molecular docking. [PDF]

open access: yesPLoS ONE
ObjectiveThis study aims to systematically investigate the molecular mechanisms through which parabens may contribute to head and neck squamous cell carcinoma (HNSCC) carcinogenesis using integrated network toxicology and molecular docking.Materials and ...
Lei Zhao   +5 more
doaj   +2 more sources

Integration of the Integrate, Design, Assess, and Share Framework in Developing the Environmental Health Literacy Toolkit Paraben-Free & Me: Protocol for a Randomized Controlled Trial [PDF]

open access: yesJMIR Research Protocols
BackgroundEndocrine-disrupting chemicals, such as parabens, are commonly found in personal care products (PCPs). Exposure to parabens is linked to several significant health risks, such as reproductive disorders, breast cancer, infertility, and hormone ...
Graziella De Michino   +2 more
doaj   +2 more sources

Ex vivo studies for the passive transdermal permeation and extent of metabolism of methyl and butyl paraben from a cream [PDF]

open access: yesBritish Journal of Pharmacy, 2017
Concerns regarding the safety of cumulative exposure to parabens have been raised as a consequence of their estrogenic and endocrine effects. These antibacterial agents are commonly used in food, pharmaceutical and cosmetic products.
Aida Hatami   +4 more
doaj   +3 more sources

Association of urine parabens with liver function in US adolescents based on NHANES 2007–2016 [PDF]

open access: yesScientific Reports
Paraben esters are commonly used as preservatives in cosmetics, personal hygiene products, food and drugs. However, there is a lack of evidence regarding the impact of exposure to Paraben esters on adolescent liver function.
Linfei Li   +4 more
doaj   +2 more sources

Parabens exposure in early pregnancy and gestational diabetes mellitus

open access: yesEnvironment International, 2019
Background: Widespread exposure to parabens has been a concern, especially among pregnant women. Only one study reported that parabens are associated with glucose levels among pregnant women. However, studies on parabens exposure and gestational diabetes
Wenyu Liu, Zongwei Cai, Hongxiu Liu
exaly   +3 more sources

Paraben Compounds—Part I: An Overview of Their Characteristics, Detection, and Impacts

open access: yesApplied Sciences, 2021
Parabens are widely used in different industries as preservatives and antimicrobial compounds. The evolution of analytical techniques allowed the detection of these compounds in different sources at µg/L and ng/L. Until today, parabens were already found
João Lincho   +2 more
doaj   +1 more source

Concentrations of urinary parabens and reproductive hormones in Iranian women: Exposure and risk assessment

open access: yesToxicology Reports, 2022
Parabens are antimicrobial preservatives in a variety of processed foods and beverages, cosmetics, pharmaceuticals, and personal care products. Parabens may be associated with reproductive and endocrine disorders among women of reproductive age.
Mohammad Malakootian   +9 more
doaj   +1 more source

Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage. [PDF]

open access: yes, 2020
During puberty, a woman's breasts are vulnerable to environmental damage ("window of vulnerability"). Early exposure to environmental carcinogens, endocrine disruptors, and unhealthy foods (refined sugar, processed fats, food additives) are hypothesized ...
Aljaber, Dana   +19 more
core   +1 more source

Parabens preferentially accumulate in metastatic breast tumors compared to benign breast tumors and the association of breast cancer risk factors with paraben accumulation

open access: yesEnvironmental Advances, 2023
Parabens are a category of antimicrobial preservatives that may play a role in the etiology and epidemiology of cancers. Parabens are employed in a wide range of pharmaceuticals, cosmetics, personal care products, and processed foods.
Craig A. Downs   +6 more
doaj   +1 more source

Toxicities of Four Parabens and Their Mixtures to and [PDF]

open access: yesEnvironmental Health and Toxicology, 2018
The objective of this study was to determine toxicities of four parabens (methyl paraben, MP; ethyl paraben, EP; n-propyl paraben, PP; and n-butyl paraben; BP) and their mixtures to two aquatic microorganisms, Daphnia magna and Aliivibrio fischeri ...
Jaewoong Lee   +3 more
doaj   +1 more source

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