Results 1 to 10 of about 1,334,386 (213)

Impact of endocrine disrupting chemicals on neurodevelopment: the need for better testing strategies for endocrine disruption-induced developmental neurotoxicity

Expert Review of Endocrinology & Metabolism, 2022
Introduction Brain development is highly dependent on hormonal regulation. Exposure to chemicals disrupting endocrine signaling has been associated with neurodevelopmental impairment.
A. Cediel-Ulloa, Diana Lupu, Y. Johansson, M. Hinojosa, F. Özel, J. Rüegg   +5 more
semanticscholar   +1 more source

Metabolic-endocrine disruption due to preterm birth impacts growth, body composition, and neonatal outcome

Pediatric Research, 2021
Despite optimized nutrition, preterm-born infants grow slowly and tend to over-accrete body fat. We hypothesize that the premature dissociation of the maternal–placental–fetal unit disrupts the maintenance of physiological endocrine function in the fetus,
Lea Sophie Möllers, Efrah I. Yousuf, Constanze Hamatschek, K. Morrison, M. Hermanussen, C. Fusch, N. Rochow   +6 more
semanticscholar   +1 more source

Prenatal exposure to phenols and benzophenones in relation to markers of male reproductive function in adulthood

Frontiers in Endocrinology, 2022
IntroductionEnvironmental exposure during fetal life may disrupt testicular development. In humans, a limited number of studies have investigated whether these adverse effects persist into adulthood.
Stine A. Holmboe, Stine A. Holmboe, Louise Scheutz Henriksen, Louise Scheutz Henriksen, Hanne Frederiksen, Hanne Frederiksen, Anna-Maria Andersson, Anna-Maria Andersson, Lærke Priskorn, Lærke Priskorn, Niels Jørgensen, Niels Jørgensen, Anders Juul, Anders Juul, Anders Juul, Jorma Toppari, Jorma Toppari, Jorma Toppari, Niels E. Skakkebæk, Niels E. Skakkebæk, Niels E. Skakkebæk, Katharina M. Main, Katharina M. Main, Katharina M. Main   +23 more
doaj   +1 more source

Endocrine-Disrupting Chemicals and Infectious Diseases: From Endocrine Disruption to Immunosuppression

International Journal of Molecular Sciences, 2021
Endocrine-disrupting chemicals (EDCs) are hormonally active compounds in the environment that interfere with the body’s endocrine system and consequently produce adverse health effects.
E. O. Adegoke, M. S. Rahman, Yoo-Jin Park, Y. J. Kim, M. Pang   +4 more
semanticscholar   +1 more source

Serum Concentrations and Gonadal Expression of INSL3 in Eighteen Males With 45,X/46,XY Mosaicism

Frontiers in Endocrinology, 2021
ObjectiveInsulin-like factor 3 (INSL3) is produced in the testes and has been proposed as a circulating biomarker of Leydig cell capacity, but remains undescribed in 45,X/46,XY mosaicism. The aim was to examine serum concentrations and gonadal expression
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Anne Jørgensen, Anne Jørgensen, Lise Aksglaede, Lise Aksglaede, John Erik Nielsen, John Erik Nielsen, Jakob Albrethsen, Jakob Albrethsen, Anders Juul, Anders Juul, Trine Holm Johannsen, Trine Holm Johannsen   +13 more
doaj   +1 more source

Serum LH/FSH ratios in 87 infants with differences of sex development

Endocrine Connections, 2023
The ratio between luteinizing hormone (LH) and follicle-stimulating hormone (FSH) has previously been described as an excellent marker of sex in healthy infants. However, LH/ FSH remains not fully described in patients with differences of sex development
Marie Lindhardt Ljubicic, Trine Holm Johannsen, Margit Bistrup Fischer, Emmie N Upners, Alexander S Busch, Katharina M Main, Anna-Maria Andersson, Casper P Hagen, Anders Juul   +8 more
doaj   +1 more source

Longitudinal evaluation of breast tissue in healthy infants: Prevalence and relation to reproductive hormones and growth factors

Frontiers in Endocrinology, 2022
IntroductionBreast tissue in infancy is a rather undescribed phenomenon. We aimed to describe the prevalence and progression of palpable breast tissue in healthy boys and girls aged 0-1 years and to evaluate clinical markers, individual serum hormone ...
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Andre Madsen, Emmie N. Upners, Emmie N. Upners, Margit Bistrup Fischer, Margit Bistrup Fischer, Alexander Siegfried Busch, Alexander Siegfried Busch, Alexander Siegfried Busch, Hanne Frederiksen, Hanne Frederiksen, Trine Holm Johannsen, Trine Holm Johannsen, Anders Juul, Anders Juul, Anders Juul, Casper P. Hagen, Casper P. Hagen   +18 more
doaj   +1 more source

The Application of Principal Component Analysis on Clinical and Biochemical Parameters Exemplified in Children With Congenital Adrenal Hyperplasia

Frontiers in Endocrinology, 2021
PurposePrincipal component analysis (PCA) is a mathematical model which simplifies data into new, combined variables. Optimal treatment of pediatric congenital adrenal hyperplasia (CAH) remains a challenge and requires evaluation of all biochemical and ...
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Andre Madsen, Andre Madsen, Andre Madsen, Anders Juul, Anders Juul, Kristian Almstrup, Kristian Almstrup, Trine Holm Johannsen, Trine Holm Johannsen   +10 more
doaj   +1 more source

Non-Classic Congenital Adrenal Hyperplasia in Two Adolescents With Gender Dysphoria

Journal of Psychosexual Health, 2021
The care of transgender individuals is multidisciplinary including medical, surgical, psychiatric, and psychological health professionals. We here report 2 cases of nonclassic congenital adrenal hyperplasia (CAH) coincidently discovered during the ...
Emma Wall, Lise Aksglaede, Mette Ewers Haahr, Peter Christiansen, Katharina M. Main   +4 more
doaj   +1 more source

In vitro investigation of endocrine disrupting effects of pesticides on Ca2+-signaling in human sperm cells through actions on the sperm-specific and steroid-activated CatSper Ca2+-channel

Environment International, 2022
Background: Ca2+-signaling controls sperm cell functions necessary for successful fertilization. Multiple endocrine disrupting chemicals have been found to interfere with normal Ca2+-signaling in human sperm cells through an activation of the sperm ...
Michala R. Birch, Mathias Johansen, Niels E. Skakkebæk, Anna-Maria Andersson, Anders Rehfeld   +4 more
doaj   +1 more source