Results 31 to 40 of about 87,528 (264)

Biochemical identification of prepubertal boys with Klinefelter syndrome by combined reproductive hormone profiling using machine learning

Endocrine Connections, 2023
Objective: Klinefelter syndrome (KS) is the most common sex chromosome disorder and genetic cause of infertility in males. A highly variable phenotype contributes to the fact that a large proportion of cases are never diagnosed.
Andre Madsen, Anders Juul, Lise Aksglaede   +2 more
doaj   +1 more source

Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children

Endocrine Connections, 2018
Introduction: Bisphenol A and several of the most commonly used phthalates have been associated with adverse metabolic health effects such as obesity and diabetes.
Amalie Carlsson, Kaspar Sørensen, Anna-Maria Andersson, Hanne Frederiksen, Anders Juul   +4 more
doaj   +1 more source

An integrative method for identification and prioritization of constituents of concern in produced water from onshore oil and gas extraction

Environment International, 2020
In the United States, onshore oil and gas extraction operations generate an estimated 900 billion gallons of produced water annually, making it the largest waste stream associated with upstream development of petroleum hydrocarbons.
Cloelle Danforth, Weihsueh A. Chiu, Ivan Rusyn, Kim Schultz, Ashley Bolden, Carol Kwiatkowski, Elena Craft   +6 more
doaj   +1 more source

Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality

Environment International, 2022
Background: Semen quality in men continues to decline in Western countries, but the contours of the issue remain obscure, in relation to contributing chemicals.
Andreas Kortenkamp, Martin Scholze, Sibylle Ermler, Lærke Priskorn, Niels Jørgensen, Anna-Maria Andersson, Hanne Frederiksen   +6 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

PFAS health effects database: Protocol for a systematic evidence map

Environment International, 2019
Background: Per- and polyfluoroalkyl substances (PFAS) confer waterproof, greaseproof, and non-stick properties when added to consumer products. They are also used for industrial purposes including in aqueous film forming foams for firefighting. PFAS are
Katherine E. Pelch, Anna Reade, Taylor A.M. Wolffe, Carol F. Kwiatkowski   +3 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome

Cell Death and Disease
Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature and immature-like Sertoli cells, and occasionally focal spermatogenesis.
Sofia B. Winge, Niels E. Skakkebaek, Lise Aksglaede, Gülizar Saritaş, Ewa Rajpert-De Meyts, Ellen Goossens, Anders Juul, Kristian Almstrup   +7 more
doaj   +1 more source

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

Endocrine Connections, 2017
Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca2+ influx into human sperm cells via the CatSper Ca2+-channel and thereby controls sperm ...
A Rehfeld, D L Egeberg, K Almstrup, J H Petersen, S Dissing, N E Skakkebæk   +5 more
doaj   +1 more source

The association between in utero exposure to maternal psychological stress and female reproductive function in adolescence: A prospective cohort study

Comprehensive Psychoneuroendocrinology, 2021
Background: Experimental studies suggest that prenatal stress affects reproductive function in female offspring, but human evidence is sparse and inconsistent. In this present study, we aim to investigate whether maternal psychological stress, quantified
E.V. Bräuner, T. Koch, D.A. Doherty, J.E. Dickinson, A. Juul, R. Hart, M. Hickey   +6 more
doaj   +1 more source