Results 31 to 40 of about 1,334,386 (213)

Distinguishing between endocrine disruption and non‐specific effects on endocrine systems

Regulatory toxicology and pharmacology : RTP, 2018
The endocrine system is responsible for growth, development, maintaining homeostasis and for the control of many physiological processes. Due to the integral nature of its signaling pathways, it can be difficult to distinguish endocrine‐mediated adverse ...
Sue M. Marty, C. Borgert, K. Coady, Richard M. Green, S. Levine, E. Mihaich, L. Ortego, J. Wheeler, K. D. Yi, L. Zorrilla   +9 more
semanticscholar   +1 more source

Endocrine-Disrupting Chemicals and Disease Endpoints

International Journal of Molecular Sciences, 2023
Endocrine-disrupting chemicals (EDCs) have significant impacts on biological systems, and have been shown to interfere with physiological systems, especially by disrupting the hormone balance.
C. Ahn, E. Jeung
semanticscholar   +1 more source

Endocrine disruption in aquatic systems: up‐scaling research to address ecological consequences

Biological Reviews of The Cambridge Philosophical Society, 2017
Endocrine‐disrupting chemicals (EDCs) can alter biological function in organisms at environmentally relevant concentrations and are a significant threat to aquatic biodiversity, but there is little understanding of exposure consequences for populations ...
F. Windsor, S. Ormerod, C. Tyler
semanticscholar   +1 more source

Butylated Hydroxyanisole (BHA) Disrupts Brain Signalling in Embryo–Larval Stage of Zebrafish Leading to Attention Deficit Hyperactivity Disorder (ADHD)

Journal of Xenobiotics
Background: Butylated hydroxyanisole (BHA) has been extensively used in several commercial industries as a preservative. It causes severe cellular and neurological damage affecting the developing fetus and might induce attention deficit hyperactivity ...
Kandhasamy Veshaal, Ramasamy Vasantharekha, Usha Rani Balu, Mahesh Vallabi Aayush, Saheshnu Sai Balaji Pillai, Winkins Santosh, Barathi Seetharaman   +6 more
doaj   +1 more source

Biochemical identification of prepubertal boys with Klinefelter syndrome by combined reproductive hormone profiling using machine learning

Endocrine Connections, 2023
Objective: Klinefelter syndrome (KS) is the most common sex chromosome disorder and genetic cause of infertility in males. A highly variable phenotype contributes to the fact that a large proportion of cases are never diagnosed.
Andre Madsen, Anders Juul, Lise Aksglaede   +2 more
doaj   +1 more source

Animal Models of Endocrine Disruption

Best practice & research. Clinical endocrinology & metabolism, 2018
Endocrine disrupting chemicals (EDCs) are compounds that alter the structure and function of the endocrine system and may be contributing to disorders of the reproductive, metabolic, neuroendocrine and other complex systems.
H. Patisaul, S. Fenton, David L. Aylor
semanticscholar   +1 more source

Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children

Endocrine Connections, 2018
Introduction: Bisphenol A and several of the most commonly used phthalates have been associated with adverse metabolic health effects such as obesity and diabetes.
Amalie Carlsson, Kaspar Sørensen, Anna-Maria Andersson, Hanne Frederiksen, Anders Juul   +4 more
doaj   +1 more source

An integrative method for identification and prioritization of constituents of concern in produced water from onshore oil and gas extraction

Environment International, 2020
In the United States, onshore oil and gas extraction operations generate an estimated 900 billion gallons of produced water annually, making it the largest waste stream associated with upstream development of petroleum hydrocarbons.
Cloelle Danforth, Weihsueh A. Chiu, Ivan Rusyn, Kim Schultz, Ashley Bolden, Carol Kwiatkowski, Elena Craft   +6 more
doaj   +1 more source

Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality

Environment International, 2022
Background: Semen quality in men continues to decline in Western countries, but the contours of the issue remain obscure, in relation to contributing chemicals.
Andreas Kortenkamp, Martin Scholze, Sibylle Ermler, Lærke Priskorn, Niels Jørgensen, Anna-Maria Andersson, Hanne Frederiksen   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source