Results 31 to 40 of about 174,481 (308)

Endocrine disrupting effects on the nesting behaviour of male three-spined stickleback Gasterosteus aculeatus L [PDF]

, 2006
The analysis of patterns of temporal variability in the nesting behaviour of male threespined stickleback (Gasterosteus aculeatus) exposed to the synthetic oestrogen, 17β-ethinylestradiol, revealed immediate, but transient, treatment-related effects ...
Borg B., Brian J. V., Nash J. P., Routledge E. J., Rowland W. J   +4 more
core   +1 more source

Presence of parabens, phenols and phthalates in paired maternal serum, urine and amniotic fluid

Environment International, 2022
Objective: To examine whether selected endocrine disrupting chemicals were present in pregnant women and passed through the placental barrier to amniotic fluid, potentially exposing the developing fetus.
Elvira V. Bräuner, Cecilie S. Uldbjerg, Youn-Hee Lim, Laura S. Gregersen, Marianna Krause, Hanne Frederiksen, Anna-Maria Andersson   +6 more
doaj   +1 more source

Dexamethasone affects human fetal adrenal steroidogenesis and subsequent ACTH response in an ex vivo culture model

Frontiers in Endocrinology, 2023
IntroductionAdministration of dexamethasone (DEX) has been used experimentally to suppress androgenization of external genitalia in 46,XX fetuses with congenital adrenal hyperplasia.
Cecilie Melau, Cecilie Melau, Berta Gayete Mor, Berta Gayete Mor, Malene Lundgaard Riis, Malene Lundgaard Riis, John E. Nielsen, John E. Nielsen, Eva Dreisler, Kasper Aaboe, Pia Tutein Brenøe, Lea Langhoff Thuesen, Kristine Juul Hare, Rod T. Mitchell, Hanne Frederiksen, Hanne Frederiksen, Anders Juul, Anders Juul, Anders Juul, Anne Jørgensen, Anne Jørgensen   +20 more
doaj   +1 more source

Obesity and endocrine-disrupting chemicals [PDF]

Endocrine Connections, 2021
Obesity is now a worldwide pandemic. The usual explanation given for the prevalence of obesity is that it results from consumption of a calorie dense diet coupled with physical inactivity. However, this model inadequately explains rising obesity in adults and in children over the past few decades, indicating that other factors must be important ...
Amato, Angelica Amorim, Wheeler, Hailey Brit, Blumberg, Bruce   +2 more
openaire   +5 more sources

Deletion in the uridine diphosphate glucuronyltransferase 2B17 gene is associated with delayed pubarche in healthy boys

Endocrine Connections, 2018
Objective: Only a few genetic loci are known to be associated with male pubertal events. The ability of excreting testosterone (T) and other steroids in the urine depends on sulfation and glucuronidation.
Annette Mouritsen, Alexander Siegfried Busch, Lise Aksglaede, Ewa Rajpert-De Meyts, Anders Juul   +4 more
doaj   +1 more source

Reduced serum concentrations of biomarkers reflecting Leydig and Sertoli cell function in male patients with congenital adrenal hyperplasia

Endocrine Connections, 2023
Congenital adrenal hyperplasia (CAH) is a recessive condition t hat affects the adrenal glands. Despite life-long replacement therapy with glucocorticoids and mineralocorticoids, adult patients with CAH often experience impaired gonadal function.
Trine Holm Johannsen, Jakob Albrethsen, Vassos Neocleous, Federico Baronio, Martine Cools, Lise Aksglaede, Niels Jørgensen, Peter Christiansen, Meropi Toumba, Pavlos Fanis, Marie Lindhardt Ljubicic, Anders Juul   +11 more
doaj   +1 more source

Environmental chemical exposures and breast cancer [PDF]

, 2016
As a hormone-sensitive condition with no single identifiable cause, breast cancer is a major health problem. It is characterized by a wide range of contributing factors and exposures occurring in different combinations and strengths across a lifetime ...
Plant, J, Stanley, E, Voulvoulis, N
core   +2 more sources

Rapid bioconcentration of steroids in the plasma of three-spined stickleback Gasterosteus aculeatus exposed to waterborne testosterone and 17β-oestradiol [PDF]

, 2007
The relationship over time between the concentrations of two steroids, singly and in combination, in a static exposure system and in the blood of three-spined stickleback Gasterosteus aculeatus, held within the exposure system was investigated. Groups of
Matthiessen, P., Maunder, R. J., Pottinger, T. G., Sumpter, J. P.   +3 more
core   +1 more source

Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]

, 2016
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M., Cotinot, C., Evans, N.P., Fowler, P.A., MacDonald, E.S., Mandon-Pepin, B., Rhind, S., Sharpe, R.M.   +7 more
core   +2 more sources

Evidence suggesting that di-n-butyl phthalate has anti-androgenic effects in fish [PDF]

, 2011
This article is the pre-print version of the full and final published article.Phthalate ester plasticizers are anti-androgenic in mammals. High doses of certain phthalates consistently interfere with the normal development of male offspring exposed in ...
Adams, Akingbemi, Autian, Bjorkblom, Borch, Culty, Dargnat, Filby, Foster, Fromme, Graham, Gray, Han, Harries, Horn, Jobling, Jobling, Jobling, Jolly, Katsiadaki, Katsiadaki, Kim, Lee, Lehmann, Liu, Loraine, Mackintosh, McCurley, Moore, Ogunfowokan, Pfaffl, Schettler, Scott, Scott, Sebire, Shen, Staples, Uren-Webster, Vethaak, Villeneuve   +39 more
core   +1 more source