Results 101 to 110 of about 14,265,842 (309)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-01-04-2019

open access: yes, 2019
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-12-07-2007

open access: yes, 2007
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-01-19-2007

open access: yes, 2007
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Columbus Free Press distribution sheet

open access: yes, 1989
This calculation sheet from February 1989 lists the distribution numbers of the Columbus Free Press at different locations around Columbus, Ohio. The Columbus Free Press began as a bi-weekly publication in Columbus, Ohio, in 1970.
Columbus Free Press (Publisher)
core  

A Hybrid Ensemble Approach for Greek Text Classification Based on Multilingual Models

open access: yesBig Data and Cognitive Computing
The present study explores the field of text classification in the Greek language. A novel ensemble classification scheme based on generated embeddings from Greek text made by the multilingual capabilities of the E5 model is presented.
Charalampos M. Liapis   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy