Results 111 to 120 of about 13,485,174 (302)

PERANCANGAN MESIN PRESS TEBU [PDF]

open access: yes, 2012
Tujuan perancangan mesin press tebu ini yaitu untuk menentukan ukuran dari setiap bagian dari mesin. Dalam perancangan ini kita juga mendapatkan rancangan transmisi pada mesin serta mengetahui pemilihan bahan dan perancangan komponen – komponen yang ...
Rio Roby , Mulyadi
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Book Reviews [PDF]

open access: yes, 1994
Abandonment of Settlements and Regions: Ethnoarchaeological and Archaeological Approaches, edited by Catherine M. Cameron and Steve A. Tomka. Cambridge University Press. 1993.
Early, Ann M., Vaughn, Heidi
core   +1 more source

IceTop - Cosmic Ray Physics with IceCube

open access: yes, 2008
The IceCube experiment at South Pole consists of two detector components - the IceTop air shower array on the surface and the neutrino telescope at depths from 1450 m to 2450 m below. Currently, 26 IceTop stations and 22 InIce strings are deployed.
Achterberg   +4 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Book reviews: On commodifying intangibles [PDF]

open access: yes, 1998
Book reviews of: 1) James Boyle, Shamans, Software, and Spleens: Law and the Construction of the Information Society. Cambridge: Harvard University Press, 1996. Pp. xvi, 270. $35.00 (cloth), $15.95 (paper).
Gordon, Wendy J., Postbrief, Sam
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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