Results 131 to 140 of about 15,901,010 (309)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-01-19-2007

open access: yes, 2007
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-01-05-2007

open access: yes, 2007
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-12-21-2018

open access: yes, 2018
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Northwest Labor Press (Print Edition)-12-15-2017

open access: yes, 2017
The Northwest Labor Press is an independent, union-supported newspaper. The print edition is mailed out twice a month to over 50,000 members of more than 80 unions in Oregon and Southwest Washington. The online edition has been maintained at nwlaborpress.
Northwest Labor Press
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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