Results 71 to 80 of about 468,087 (314)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Pontiac Press newspaper scanned from microfilmPontiac Motor part of GM expansion plan: Part of billion to be allocated for local plant ; Steel industry planning enormous expansion ; Two-passenger sports model is Pontiac's latest creation ; Fascinating ...
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Public health and landfill sites [PDF]
Landfill management is a complex discipline, requiring very high levels of organisation, and considerable investment. Until the early 1990’s most Irish landfill sites were not managed to modern standards.
Staines, Anthony +4 more
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FORMATION OF EFFICIENCY OF NORTHERN CASPIAN SEA
Northern part of Caspian sea is the richest on biological efficiency. Rich with biogene elements and an organic substratum of water of Northern Caspian sea render a great influence on a variety of flora and fauna of all Caspian sea.
N. G. Shaboyants, S. V. Shipylin
doaj +1 more source
Synthesis of Functional Oxides Using Cubic Anvil Press—BiNiO3 Exhibiting Inter-site Charge Transfer—
High-pressure synthesis is a powerful technique in searching for new materials. We have found a large number of functional oxides using this technique. BiNiO3 is a distorted perovskite compound with unusual Bi1/23+Bi1/25+Ni2+O3 valence state. High-pressure neutron diffraction measurements and bond valence sum calculations show that the pressure-induced
AZUMA, Masaki +3 more
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Pontiac Press newspaper scanned from microfilmViet shellings anger US ; Lunar module passes jolt test ; City mass picketing restrained by court ; Plane crash kills 2, Troy airport closed ; Legislators join outcry on ABM ; Nixon previews report to nation ;
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Are vaccination sites in Bangladesh scale efficient? [PDF]
OBJECTIVES: The overall aim of this study is to discern whether and to what degree vaccination sites exhibit constant returns to scale. METHODS: Data Envelopment Analysis is used to compare all the facilities in the sample in terms of input costs used to
Fox-Rushby, Julia +5 more
core +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Pontiac Press newspaper scanned from microfilmLaos, N-ban are barriers: June summit talks possible ; Progress is the word for it ; Sites suitable to U.S.: Vienna or Stockholm ; LBJ gets word Red regime in China toppling ; Star’s body lies in state: world
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