Results 31 to 40 of about 2,964,539 (266)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Oscillatory mechanoluminescence of Mn2+-doped SrZnOS in dynamic response to rapid compression

Nature Communications
Photon emission may be continuously produced from mechanical work through self-recoverable mechanoluminescence (ML). Significant progress has been made in high-performance ML materials in the past decades, but the rate-dependent ML kinetics remains ...
Hao Wang, Tingting Zhao, Mei Li, Junlong Li, Ke Liu, Shang Peng, Xuqiang Liu, Bohao Zhao, Yanlong Chen, Jiao An, Xiaohui Chen, Sheng Jiang, Chuanlong Lin, Wenge Yang   +13 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Under pressure

Nature Reviews Microbiology, 2020
If we aren't sure what causes hypertension, should we really be medicating it, wonders Peter Judge.
openaire   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

NbN-based Josephson junctions grown by plasma-assisted molecular beam epitaxy

Communications Materials
Improved process for the growth of NbN by plasma-assisted molecular beam epitaxy (PAMBE) is needed for the fabrication of Josephson junctions, that are building blocks of qubits in quantum computers.
Artur Lachowski, Paweł Wolny, Krzysztof Dybko, Mikołaj Chlipała, Krzesimir Nowakowski-Szkudlarek, Mateusz Hajdel, Mikołaj Żak, Anna Feduniewicz, Marta Sawicka, Witold Chromiński, Ewa Grzanka, Czesław Skierbiszewski   +11 more
doaj   +1 more source

Toughening of silicon nitride ceramics through stress-induced phase transformation

Journal of Advanced Ceramics
Ceramics, particularly covalently bonded ceramics, exhibit intrinsic brittleness resulting from the strong directional nature of their chemical bonds, significantly limiting their applications.
Shucheng Liu, Yue Pan, Bingtao Feng, Baoyin Xu, Kuo Hu, Xiaojun Xiang, Leiming Fang, Xiaohong Yuan, Qiang Tao, Pinwen Zhu, Zhaodong Liu, Hu Tang, Bingbing Liu   +12 more
doaj   +1 more source

Pressure-Induced Polymerization: Addition and Condensation Reactions

Molecules, 2021
Under pressure of 1–100 GPa, unsaturated organic molecules tend to form covalent bond to each other for a negative enthalpy change, which often produces polymeric materials with extended carbon skeleton.
Fang Li, Jingqin Xu, Yajie Wang, Haiyan Zheng, Kuo Li   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source