Results 41 to 50 of about 2,964,539 (266)

Recent advances in high-pressure science and technology

open access: yesMatter and Radiation at Extremes, 2016
Recently we are witnessing the boom of high-pressure science and technology from a small niche field to becoming a major dimension in physical sciences.
Ho-Kwang Mao   +6 more
doaj   +1 more source

Nested order-disorder framework containing a crystalline matrix with self-filled amorphous-like innards

open access: yesNature Communications, 2022
The synthesis and characterization of new crystalline-amorphous hybrid materials is challenging. Here, the authors report the preparation of a nested order-disorder framework by applying high pressure to a nested copper chalcogenide Cu12Sb4S13.
Kejun Bu   +13 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Effect of microstructure refinement of pure copper on improving the performance of electrodes in electro discharge machining (EDM)

open access: yesScientific Reports, 2023
The paper presents an analysis of the impact of plastic deformation using hydrostatic extrusion (HE) on the structural, mechanical and functional properties of pure copper for use as electrodes in the process of electro discharge machining (EDM). As part
Jacek Skiba   +5 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

From Molecules to Carbon Materials—High Pressure Induced Polymerization and Bonding Mechanisms of Unsaturated Compounds

open access: yesCrystals, 2019
With the development of high-pressure apparatus, in situ characterization methods and theoretical calculations, high-pressure technology becomes a more and more important method to synthesize new compounds with unusual structures and properties.
Xin Yang   +4 more
doaj   +1 more source

Price pressures [PDF]

open access: yesJournal of Financial Economics, 2014
We study price pressures, i.e., deviations from the efficient price due to risk-averse intermediaries supplying liquidity to asynchronously arriving investors. Empirically, New York Stock Exchange intermediary data reveals economically large price pressures, 0.49% on average with a half life of 0.92 days. Theoretically, a simple dynamic inventory model
Hendershott, Terrence   +1 more
openaire   +5 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Pressure stabilizes ferrous iron in bridgmanite under hydrous deep lower mantle conditions

open access: yesNature Communications
Earth’s lower mantle is a potential water reservoir. The physical and chemical properties of the region are in part controlled by the Fe3+/ΣFe ratio and total iron content in bridgmanite.
Li Zhang   +7 more
doaj   +1 more source

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