Results 81 to 90 of about 5,609,198 (311)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Successful treatment of postoperative, radiation-associated wound dehiscence around tracheostomy with negative pressure wound therapy. [PDF]

, 2018
We present case report of 62-year-old man who underwent total laryngectomy, bilateral neck dissection and radiotherapy due to laryngeal cancer. After 11 months he was reoperated because of a local recurrence.
Kukwa, Wojciech, Walczak, Dominik, Migacz, Ewa, Maciejewski, Adam   +3 more
core   +1 more source

Redox reactions in subducted CaCO3–Fe–SiO2 as a potential source of superdeep diamond inclusions

Scientific Reports
CaCO3 is one of the most abundant carbonates at the Earth’s surface. It is transported into the mantle in substantial quantities via subducted slabs and participates in the deep mantle carbon cycle along with other mantle materials.
Mengqi Guo, Xinyang Li, Zhu Mao, Fangfei Li, Liang Li, Qiang Zhou   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Intra-operative pressure sores [PDF]

, 1995
As the extent of the pressure sore problem within hospitalized populations has been realized, their costs estimated and changes in the management of the NHS occurred, interest in pressure sores has increased and focused toward prevention.
Bridel, Jane Elizabeth
core  

Pressure-driven crystal symmetry and carrier concentration optimization for superior thermoelectric transport properties in layered AgCrSe2 [PDF]

Matter and Radiation at Extremes
Phase engineering has proven to be an effective strategy for achieving superior thermoelectric performance, while pressure is an excellent means of expanding the phase space of a material. In this paper, the effect of pressure-induced phase transition on
Zheng Bi, Dianzhen Wang, Yiyang Zhou, Yang Gao, Jing Zou, Fuyang Liu, Qiang Tao, Bin Yang, Huijuan Yue, Luhong Wang, Haozhe Liu, Yan Li, Pinwen Zhu   +12 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Application of machine learning for nanodiamonds shape and surface classification based on X-ray pattern analysis

Scientific Reports
Three Machine Learning algorithms, namely Random Forest, Neural Networks and Extreme Gradient Boosting, were applied to recognize the shape and surface structure of diamond nanoparticles from powder diffraction data.
Kazimierz Skrobas, Kamila Stefańska-Skrobas, Svitlana Stelmakh, Stanisław Gierlotka, Bogdan Palosz   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source