Results 191 to 200 of about 24,188,873 (354)
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods
Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled; Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon +22 morewiley +1 more sourceBasilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods
In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix +38 morewiley +1 more sourceFibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group +28 morewiley +1 more sourceCost‐Effectiveness of Intensive versus Standard Blood‐Pressure Control
New England Journal of Medicine, 2017 A. Bress, B. Bellows, Jordan B. King, R. Hess, S. Beddhu, Zugui Zhang, D. Berlowitz, M. Conroy, Lawrence J. Fine, S. Oparil, D. Morisky, L. Kazis, N. Ruiz‐Negrón, James R. Powell, L. Tamariz, J. Whittle, J. Wright, M. Supiano, A. Cheung, W. Weintraub, Andrew E. Moran +20 moresemanticscholar +1 more sourceChanges in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background
Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers' Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen +11 morewiley +1 more sourceBlood Pressure Polygenic Score Predicts Long-Term Blood Pressure Control and Treatment-Resistant Hypertension. [PDF]
HypertensionCho SMJ, Ruan Y, Lee HH, Koyama S, Juraschek SP, Allen NB, Yang E, McEvoy JW, Secemsky E, Honigberg MC, Fahed AC, Patel A, Hornsby WE, Natarajan P. +13 moreeuropepmc +1 more sourceInfluence of Baseline Diastolic Blood Pressure on Effects of Intensive Compared With Standard Blood Pressure Control
Circulation, 2018 S. Beddhu, Glenn M. Chertow, Alfred K. Cheung, W. Cushman, Mahboob Rahman, Tom Greene, Guo Wei, Ruth C. Campbell, Margaret Conroy, Barry I. Freedman, William Haley, Edward J. Horwitz, D. Kitzman, J. Lash, V. Papademetriou, R. Pisoni, Erik Riessen, Clive Rosendorff, Suzanne G. Watnick, J. Whittle, P. Whelton +20 moresemanticscholar +1 more source