Results 41 to 50 of about 2,724,057 (240)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Distortion mechanisms in varactor diode-tuned microwave filters [PDF]

open access: yes, 2006
This paper examines the broadband distortion behavior in flexible filters employing varactor-diode tuning elements. Series- and parallel-resonant varactor-loaded transmission-lines, both commonly used in bandpass and bandstop microwave filters, are ...
Carey-Smith, BE, Warr, PA
core   +1 more source

Strip distortion generator for simulating inlet flow distortion in gas turbine engine ground test facilities

open access: yesPropulsion and Power Research, 2016
A methodology has been developed to generate a non-uniform/distorted inlet flow field to test a gas turbine engine in ground test facilities. The distorted flow field is generated by positioning radial and circumferential strips of varying widths ...
M. Saleem Yusoof   +2 more
doaj   +1 more source

Harmonic Forcing from Distortion in a Boundary Layer Ingesting Fan

open access: yesAerospace, 2021
Integrating a fan with a boundary layer ingestion (BLI) configuration into an aircraft fuselage can improve propulsion efficiency by utilizing the lower momentum airflow in the boundary layer developed due to the surface drag of the fuselage.
Hans Mårtensson
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

A Numerical Study on the Impact of Dynamic Distortions in Total Inlet Pressure on the Stability and Performance of an Aero-Engine's Axial Fan [PDF]

open access: yesفناوری در مهندسی هوافضا
In preliminary jet engine design, uniform inlet conditions are typically assumed for the compression section, although real-world engines operate under non-uniform inflows that significantly affect the compressor and overall engine performance.
mostafa mahmoodi   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Predicting weld distortion in the design of automotive components [PDF]

open access: yes, 2007
This project was set up in order to investigate whether it may be valid to use a simplified approach to weld distortion prediction in order to make an assessment of the distortions occurring in a welded structure.
O'Brien, Roger William
core  

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