Results 111 to 120 of about 4,038,581 (311)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Development of Pant-Type Harness with Fabric Air-Pocket for Pain Relief

Applied Sciences, 2019
Harnesses can be used in various applications, such as entertainment, rescue operations, and medical applications. Because users are supported on the harness for a long time, they should feel comfortable wearing the harnesses.
Dongwoo Nam, Miyeon Kwon, Juhea Kim, Bummo Ahn   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Investigation on the Impact Resistance of Bridge Piers with a Reinforced Concrete Composite Structure Against Debris Flow

Buildings
Round-ended bridge piers are specifically utilized for high-speed railways in mountainous areas. However, the protective measures for such piers under debris flow remain limited, especially regarding the various components in the debris flow.
Yinsheng Wang, Yongqiang Li, Honggang Wu, Yongchao Li, Jing Li, Baolong Zhu   +5 more
doaj   +1 more source

Characteristics of Modified Spiral Thrust Bearing through Geometries and Dimension Modifications

Tribology Online, 2018
This research focuses on the optimum design of fluid dynamic bearing (FDB) named modified spiral design. The objective is to improve the pressure and velocity distribution inside the FDB.
Mohd Danial Ibrahim, Norliza Marusman, Yuta Sunami, Siti Nur Azizah Amran, Saad Salahuddin Musa, Masayuki Ochiai, Su Shiung Lam   +6 more
doaj   +1 more source

Blood pressure distribution in microvascular networks [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Fonta, C, Guibert, R, Plouraboue, F   +3 more
core  

Measurement of the small-scale structure of the intergalactic medium using close quasar pairs

, 2017
The distribution of diffuse gas in the intergalactic medium (IGM) imprints a series of hydrogen absorption lines on the spectra of distant background quasars known as the Lyman-$\alpha$ forest.
Hennawi, Joseph F., Kulkarni, Girish, Lee, Khee-Gan, Lukić, Zarija, Oñorbe, Jose, Prochaska, J. Xavier, Rorai, Alberto, Walther, Michael, White, Martin   +8 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Active control of flows around a bluff body with yaw angle by inducing longitudinal vortices using plasma actuators

Nihon Kikai Gakkai ronbunshu
Active control of flow separation on a bluff body model utilizing dielectric barrier discharge plasma actuators (DBD-PAs) was experimentally demonstrated at Re = 28,000. The model consisting of a flat side plate and a quarter cylinder with a radius of 84.
Ryuya IMAI, Takehiko SEGAWA
doaj   +1 more source

Computer program MCAP-TOSS calculates steady-state fluid dynamics of coolant in parallel channels and temperature distribution in surrounding heat-generating solid [PDF]

, 1967
Computer program calculates the steady state fluid distribution, temperature rise, and pressure drop of a coolant, the material temperature distribution of a heat generating solid, and the heat flux distributions at the fluid-solid interfaces.
Lee, A. Y.
core   +1 more source