Results 91 to 100 of about 8,297,853 (296)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Control of two-dimensional offset jet using burst modulation with a plasma actuator
Nihon Kikai Gakkai ronbunshu, 2018 An experimental study is performed on a two-dimensional offset jet with a dielectric barrier discharge plasma actuator (PA) as a flow control device that introduces a periodic disturbance to the system. The offset jet is produced by a flow of air emitted
Shu SASAKI +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Body-cushion contact pressure distribution cloud map.
, 2023 Body-cushion contact pressure distribution cloud map.
Jifeng Lian (14609705) +2 more
core +1 more source
Effect of the contact pressure on the fretting of railway axle journal bearings
Nihon Kikai Gakkai ronbunshu, 2016 The fretting wear is caused by the very slight relative slip between the contacting surfaces of the inner ring side face and the backing ring of an axle journal bearing in railway applications, but its mechanism is not clear.
Yoshiaki OKAMURA +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Characteristics of Welding and Arc Pressure in the Plasma–TIG Coupled Arc Welding Process
Metals, 2018 In this article, a novel hybrid welding process called plasma-TIG (Tungsten Inert Gas welding) coupled arc welding was proposed to improve the efficiency and quality of welding by utilizing the full advantage of plasma and TIG welding processes.
Bo Wang +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Electron energy distribution function in low-pressure complex plasmas
, 2005 The effect of density and size of dust grains on the electron energy distribution function (EEDF) in low-temperature complex plasmas is studied. It is found that the EEDF depends strongly on the dust density and size.
Ostrikov, K. +3 more
core +1 more source