Results 91 to 100 of about 7,952,101 (296)
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Experimental Study of Railway Trackbed Pressure Distribution Under Dynamic Loading
The Baltic Journal of Road and Bridge Engineering, 2019 Reliable and durable operation of the railway track under the dynamic load of the rolling stock depends considerably on the ability of the ballast layer to get the load from the sleepers and distribute it to the subgrade.
Mykola Sysyn +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Experimental Investigation of Pressure Distribution Along Makhool Dam Spillway
Diyala Journal of Engineering Sciences, 2013 This research is an experimental investigation on the pressure distribution along the surface of Makhool Dam spillway. The work is carried out as series of tests; these series are on the model as it is designed.
Muhanad Mohammed Abbas
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
World Electric Vehicle JournalWith the rapid development of electric vehicles, the safety and reliability of lithium-ion batteries (LIBs), as their core energy storage units, have become increasingly prominent. The variation in internal battery pressure is closely related to critical
Qingyun Liu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Journal of Applied Science and EngineeringMost studies conducted in the indoor unit of water-cooled air conditioners focus on increasing its efficiency and reducing its temperature. The purpose of this study is to conduct a numerical simulation of a centrifugal fan with forward blades using the ...
Yingying Zhang
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source