Results 51 to 60 of about 91,606 (298)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Non-parametric models in the monitoring of engine performance and condition: Part 1: modelling of non-linear engine processes

open access: yes, 1999
This paper proposes the use of radial basis function (RBF) networks in the modelling of non-linear engine processes. A pertinent application of such a model is the reconstruction of cylinder pressure based upon the instantaneous angular velocity of the ...
Jacob, P J, Gu, Fengshou, Ball, Andrew
core   +1 more source

Numerical Investigation of Periodically Unsteady Pressure Field in a High Power Centrifugal Diffuser Pump

open access: yesAdvances in Mechanical Engineering, 2014
Pressure fluctuations are the main factors that can give rise to reliability problems in centrifugal pumps. The periodically unsteady pressure characteristics caused by rotor-stator interaction have been investigated by CFD calculation in a residual heat
Ji Pei   +3 more
doaj   +1 more source

Evolution Law of Wellbore Instability Risk under Fluctuating Pressure

open access: yesEnergies, 2023
The bottom hole fluctuating pressure has a large influence on the wellbore instability. To address this problem, firstly, according to the principle of seepage mechanics, we established a calculation model of the change in pore pressure around the ...
Kai Zhao   +4 more
doaj   +1 more source

Fluctuation of Blood Pressure in a Patient With Pheochromocytoma

open access: yesJACC: Case Reports, 2020
Treatment with a combination of norepinephrine and doxazosin was effective in a patient with pheochromocytoma who had blood pressure fluctuation, hypotension, and recurrent syncope. After adrenalectomy, his blood pressure, heart rate, and plasma levels of catecholamines remained normal and stable without any medication. (Level of Difficulty: Beginner.).
Yuichi Fujii, MD, PhD   +5 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Mechanism Analysis on the Fluctuation of Linear Compressor in Refrigerator

open access: yesZhileng xuebao, 2019
The experimental results of a refrigerator system with linear compressor showed that there was a period of piston stroke fluctuation as the supply power remained unchanged after an initial start-up adjustment.
Zou Huiming   +3 more
doaj  

Experimental Research and Numerical Analysis of Pressure Fluctuation Characteristics of Rim Driven Propulsion Pump Outlet

open access: yesMachines, 2021
The pressure fluctuation characteristics of a rim driven propulsion pump are studied by an experimental method firstly, and then its unsteady inner flow is studied by numerical simulation to reveal the generating mechanism of the pressure fluctuation. In
Zhipeng Zhu, Houlin Liu
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Towards Self-Powered Devices Via Pressure Fluctuation Energy Harvesters

open access: yes, 2021
The growing interest in the Internet of Things has created a need for wireless sensing systems for industrial and consumer applications. In hydraulic systems, a widely used method of power transmission in industry, wireless condition monitoring can lead ...
Aranda, Jesus Javier Lechuga
core  

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