Results 71 to 80 of about 87,970 (262)

Detecting Pressure Waves during Earthquakes in an In-Service Pipeline System for Agricultural Irrigation using Numerical Analysis

open access: yese-Journal of Nondestructive Testing
Seismic hydrodynamic pressure, which is burst water pressure fluctuation induced by earthquakes, is often observed in water pipelines. The earthquake damage includes detachment and damage to pneumatic valves in curved pipe sections, and we believe that ...
Taiki Hagiwara   +2 more
doaj   +1 more source

Semi-diurnal pressure fluctuation in the ERA40 Data

open access: yesMeteorologische Zeitschrift, 2007
In a regional analysis the removal of the globally present semi-diurnal pressure signal could be necessary in order to isolate the pressure signal of regional features.
Klaus P. Hoinka
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Large Eddy Simulation for Fluctuation Pressure of High Speed Train Head Surface

open access: yes工程科学与技术, 2009
: In order to obtain the distribution rules of fluctuation pressure of train head surface, body-fitted quadrilateral and hexahedron grid was obtained of high speed train head surface based on parameter space mapping approach.
doaj  

LSTM Reconstruction of Turbulent Pressure Fluctuation Signals

open access: yesComputation
This paper concerns the application of a long short-term memory model (LSTM) for high-resolution reconstruction of turbulent pressure fluctuation signals from sparse (reduced) data.
Konstantinos Poulinakis   +4 more
doaj   +1 more source

Design of Adaptive Negative Pressure Regulating System for Glass Solidification of HLLW by Cold Crucible

open access: yesYuanzineng kexue jishu, 2022
During the operation of twostep cold crucible glass solidification device, the pressure control of cold crucible and calciner is very important. However, due to the periodic decomposition or sealing problem of calcined products, there will be large ...
WANG Zexue;LI Baojun;LI Yusong;QIE Dongsheng
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Experimental study on the flow structure and sound generation between the blades of multi-blade fan

open access: yesNihon Kikai Gakkai ronbunshu, 2017
The relationship between flow structure and generation of aerodynamic sound from a multi-blade fan is experimentally investigated with enlarged two-dimensional blade models. Two blade models with different shapes are used.
Koji IWANO   +8 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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