Results 81 to 90 of about 91,606 (298)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Influences on Bottom Hole Pressure in Riserless Drilling under Platform Disturbance

open access: yesShiyou jixie, 2022
In order to solve the problem of bottom hole pressure fluctuation caused by drilling platform disturbance in riserless drilling,a mathematical model for platform-drill string coupling vibration and a model for bottom hole pressure fluctuation were ...
Zuo Kai   +3 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Analysis of unsteady cavitating flow and pressure fluctuation around highly skewed propeller in non-uniform wake

open access: yes, 2016
Numerical simulation of an unsteady cavitating flow around a highly skewed propeller in a non-uniform wake is performed based on an explicit LES approach with k subgrid model.
王一伟   +5 more
core  

Numerical Calculation of the Influence of Working Conditions and Rotational Speed on Pressure Pulsation of a Self‐Priming Pump

open access: yesEnergy Science & Engineering
To accurately determine the pressure fluctuation characteristics of a specific self‐priming pump, a full three‐dimensional computational model was established, including the S‐tube, impeller domain, volute domain, gas‐liquid separation chamber, front and
Hai‐Bing Jiang   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Detecting Pressure Waves during Earthquakes in an In-Service Pipeline System for Agricultural Irrigation using Numerical Analysis

open access: yese-Journal of Nondestructive Testing
Seismic hydrodynamic pressure, which is burst water pressure fluctuation induced by earthquakes, is often observed in water pipelines. The earthquake damage includes detachment and damage to pneumatic valves in curved pipe sections, and we believe that ...
Taiki Hagiwara   +2 more
doaj   +1 more source

Pressure fluctuation–vortex interaction in an ultra-low specific-speed centrifugal pump

open access: yesJournal of Low Frequency Noise, Vibration and Active Control, 2019
To provide a comprehensive understanding of the pressure fluctuation–vortex interaction in non-cavitation and cavitation flow, in this article, the unsteady flow in an ultra-low specific-speed centrifugal pump was investigated by numerical simulation ...
Cong Wang   +5 more
doaj   +1 more source

Numerical analysis of pressure fluctuation in a multiphase rotodynamic pump with air–water two-phase flow

open access: yesOil & Gas Science and Technology, 2019
Pressure fluctuation in single-phase pumps has been studied widely, while less attention has been paid to research on multiphase pumps that are commonly used in the petroleum chemical industry.
Zhang Wenwu   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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