Results 61 to 70 of about 3,583,341 (309)

The Effect of Thixotropy on Pressure Losses in a Pipe

open access: yesEnergies, 2020
Drilling fluids are designed to be shear-thinning for limiting pressure losses when subjected to high bulk velocities and yet be sufficiently viscous to transport solid material under low bulk velocity conditions.
Eric Cayeux, Amare Leulseged
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Bypass, Loss, and Heat Transfer in Aircraft Surface Coolers

open access: yesFrontiers in Mechanical Engineering, 2019
Surface coolers are heat exchangers with fins on the air side. When air approaches the fins, a portion is diverted away (bypass) because of the adverse pressure gradients induced by the fins.
Jason Liu   +4 more
doaj   +1 more source

Metallic diffusion measured by a modified Knudsen technique [PDF]

open access: yes, 1969
Diffusion coefficient of a metal in high temperature system is determined. From the measurement of the weight loss from a Knudsen cell, the vapor pressure of the escaping species can be calculated.
Fray, D. J.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Effective operation investigation of unglazed solar air collector / Neįstiklinto orinio saulės kolektoriaus efektyvaus veikimo tyrimas

open access: yesMokslas: Lietuvos Ateitis, 2016
The article presents results of an effective operation analysis of VGTU Environmental Engineering Faculty southern facade integrated unglazed transpired solar collector.
Dovydas Rimdžius   +2 more
doaj   +1 more source

Unsteady adjoint of pressure loss for a fundamental transonic turbine vane

open access: yes, 2015
High fidelity simulations, e.g., large eddy simulation are often needed for accurately predicting pressure losses due to wake mixing in turbomachinery applications.
Laskowski, Gregory M.   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

IFC-based performance data checking for ventilation system design

open access: yesJournal of Asian Architecture and Building Engineering, 2023
With the development of Building information modelling (BIM) tools, the non-geometric attributes of duct elements, such as size, flow rate, and pressure loss, can be exported directly. BIM has been used in numerous building projects. However, there is no
Lei Xu, Yoshinobu Adachi
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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