Results 71 to 80 of about 3,560,028 (306)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

IFC-based performance data checking for ventilation system design

open access: yesJournal of Asian Architecture and Building Engineering, 2023
With the development of Building information modelling (BIM) tools, the non-geometric attributes of duct elements, such as size, flow rate, and pressure loss, can be exported directly. BIM has been used in numerous building projects. However, there is no
Lei Xu, Yoshinobu Adachi
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Web-based approach for systematic analysis and interactive visualization of the industry foundation classes data: a case study in duct design

open access: yesJournal of Asian Architecture and Building Engineering, 2023
Existing model checkers of building information modeling (BIM) can open industry foundation classes (IFC) files and perform clash detection between mechanical, electrical, and plumbing (MEP) and architectural as well as structural models.
Hongxia Deng   +4 more
doaj   +1 more source

Gas diffuser facilitates withdrawal of cryogenic liquids from tanks [PDF]

open access: yes, 1966
Compact, cylindrical gas diffuser with radial exhaust slots and internal axial flow channels maintains the necessary pressure for the desired withdrawal rate of cryogenic liquids from tanks.
Dunn, J. D.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

RADIATOR DESIGN AS PART OF BEAMFORMER RACK

open access: yesВестник Донского государственного технического университета, 2018
The design-engineering techniques to improve hydraulic and, accordingly, thermal characteristics of the liquid cooling radiator of the communications-electronics equipment (CEE) beamformer rack are presented.
Leyla Vladimirovna Glazunova   +1 more
doaj  

Development and Experimental Study of the First Stage in a Two-Stage Water-Flooded Single-Screw Compressor Unit for Polyethylene Terephthalate Bottle Blowing System

open access: yesEnergies, 2020
The oil-free compressor is a key component in fabricating polyethylene terephthalate (PET) bottles for beverages and water. At present, the main compressor type used for blowing PET bottles is the reciprocating compressor.
Ting Li   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Full Surface Heat Transfer Characteristics of Stator Ventilation Duct of a Turbine Generator

open access: yesEnergies, 2020
Turbine generators operate with complex cooling systems due to the challenge in controlling the peak temperature of the stator bar caused by Ohm loss, which is unavoidable.
Shinyoung Jeon   +4 more
doaj   +1 more source

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