Results 51 to 60 of about 11,875,396 (307)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Flipped learning to enhance self-efficacy and training satisfaction in pressure injury management: a commentary [PDF]
Commentary on: Chao, W.Y. and Liao, W. C.Liao, W. C. (2025). Long-Term Effects of Flipped Learning on Nurses’ Self-Efficacy and Satisfaction in Pressure Injury Management: A Multi-Center Quasi-Experimental Study. 85, 104 368.
Sorice, V., Gould, J.
core +1 more source
Engineering ProceedingsSectorization and pressure management are techniques that simplify leak detection and its control in water networks. This article proposes a novel three-stage methodology.
Melina Denardi +3 more
doaj +1 more source
A Field data- based method to determine the pressure-burst relationships in urban water distribution networks [PDF]
علوم محیطی, 2018 Introduction: One of the challenges facing water and wastewater companies around the world is water loss from water distribution networks following after burst and leakage, which imposes high economic, social and environmental costs on these companies ...
Yasaman Taj Abadi +2 more
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
EnergiesUrban water distribution systems face growing challenges from energy inefficiencies caused by hydraulic anomalies, such as pipe aging, bursts, demand variability, and suboptimal pump and valve operations.
Bowen Duan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Information systems management maturity and information technology security effectiveness [PDF]
, 2004 vii, 129 leaves ; 29 cm.Modern societies rely on Information Systems (IS), yet their protection has long been considered ineffective. Researchers and practitioners have struggled to understand the persistence of this phenomenon, but both agree that IS ...
Spicer, Garry +1 more
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source