Results 71 to 80 of about 1,171,660 (315)

Anesthetic management of late pressure angioedema

Revista Brasileira de Anestesiologia, 2017
Background and objectives: Late pressure angioedema is a rare form of angioedema in which light pressure stimulus can lead to edema after 1-12 h. This uncommon and unreported entity is especially important in patients who undergo general anesthesia, for ...
Inês Furtado, Filipe Linda, Sílvia Pica, Marco Monteiro   +3 more
doaj   +3 more sources

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

High-Energy-Low-Temperature Technologies for the Synthesis of Nanoparticles: Microwaves and High Pressure

Inorganics, 2014
Microwave Solvothermal Synthesis (MSS) is a chemical technology, where apart from possible effects of microwaves on the chemical reaction paths, microwave heating allows the precise planning of a time-temperature schedule, as well as to achieve high ...
Witold Lojkowski, Cristina Leonelli, Tadeusz Chudoba, Jacek Wojnarowicz, Andrzej Majcher, Adam Mazurkiewicz   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Age‐Related Trends in Home Blood Pressure, Home Pulse Rate, and Day‐to‐Day Blood Pressure and Pulse Rate Variability Based on Longitudinal Cohort Data: The Ohasama Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Home blood pressure is a more accurate prognosticator than office blood pressure and allows the observation of day‐to‐day blood pressure variability.
Michihiro Satoh, Hirohito Metoki, Kei Asayama, Takahisa Murakami, Ryusuke Inoue, Megumi Tsubota‐Utsugi, Ayako Matsuda, Takuo Hirose, Azusa Hara, Taku Obara, Masahiro Kikuya, Kyoko Nomura, Atsushi Hozawa, Yutaka Imai, Takayoshi Ohkubo   +14 more
doaj   +1 more source

Blood Pressure and Chronic Kidney Disease Stratified by Gender and the Use of Antihypertensive Drugs

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background The present study assessed the association between blood pressure (BP) and the risk of chronic kidney disease (CKD) according to gender and the use of antihypertensive drugs using data from a large‐scale health checkup.
Michihiro Satoh, Takuo Hirose, Shingo Nakayama, Takahisa Murakami, Kyosuke Takabatake, Kei Asayama, Yutaka Imai, Takayoshi Ohkubo, Takefumi Mori, Hirohito Metoki   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Peer Pressure and Manager Pressure in Organisations *

We study the interaction between horizontal (peer) and vertical (manager) social factors in workers’ motivation. In our setting, individuals work using open-plan desks. Using a natural experiment, we identify a sharp increase in workers’ productivity following the occupation of adjacent desks. We link this peer pressure effect to two key aspects of the
Battiston, Diego, Blanes i Vidal, Jordi, Kirchmaier, Tom, Szemeredi, Katalin   +3 more
openaire   +2 more sources