Results 151 to 160 of about 9,220,032 (239)

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

Anion–π Interaction‐Regulated Ion Generation and High Piezoionic Response in Ultrasoft Low‐Salinity Hydrogels

Angewandte Chemie, EarlyView.
The first hydrogel system employing anion–π interactions as a central design motif is developed. The cooperative aromatic–phosphate interaction motif provides dynamic cohesion and is proposed to regulate the separation and transport of water‐derived ionic species, achieving high piezoionic response in injectable, self‐healing, ultrasoft, low‐salinity ...
Jinyang Jiang, Jiawen Zhang, Binglin Zhou, Xiaotian Wang, Lei Ding, Mingfei Pan, Fengjuan Wang, Zhiyong Liu, Qiongyao Peng, Chenyu Qiao, Li Xiang, Hongbo Zeng   +11 more
wiley   +2 more sources

Tidal swings of endotracheal tube cuff pressure during pressure support ventilation: A CARE-compliant case report. [PDF]

Medicine (Baltimore)
Zhang RZ, Xu SS, Miao MY, Liu HY, Yue YL, Zhou JX.   +5 more
europepmc   +1 more source

An investigation on the respiratory mechanics of mechanically ventilated patients during spontaneous breathing trials with enhanced low-level pressure support ventilation. [PDF]

Clin Respir J, 2023
Zhang B, Zhang Z, Qin H, Jiang Z, Deng Q, Sun Q, Wang Y, Zhou J, Lin Z, He W, Hua D, Xu Y.   +11 more
europepmc   +1 more source

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

Animal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang, Xuepei Lei, Yiying Huang, Jiaming Tang, Guiying Shi, Hang Li, Lin Bai   +6 more
wiley   +1 more source

Removal of cardiogenic oscillations during pressure support ventilation using sliding window singular spectrum analysis: proof-of-concept. [PDF]

Biomed Eng Online
Pagano PP, Ciaccio EJ.
europepmc   +1 more source

Validation of the flow index to detect low inspiratory effort during pressure support ventilation. [PDF]

Ann Intensive Care, 2022
Miao MY, Chen W, Zhou YM, Gao R, Song DJ, Wang SP, Yang YL, Zhang L, Zhou JX.   +8 more
europepmc   +1 more source

Repeated instillations of bleomycin in male mice induce a perivascular remodeling at distance of fibrotic areas in the context of progressive pulmonary fibrosis

Animal Models and Experimental Medicine, EarlyView.
We established a model of progressive pulmonary fibrosis via repeated intratracheal instillation (ITI) of leomycin (BLM) (A). Perivascular remodeling was observed in areas distant from the fibrotic areas and lesions induced by repeated ITI of BLM simulate those observed in IPF patients (B). Thus, this model has the capacity to track and investigate the
Céline‐Hivda Yegen, Zakaria Maakoul, Dominique Marchant, Patrice Callard, Julia Bourse, Jean‐François Bernaudin, Hilario Nunes, Carole Planès, Emilie Boncoeur, Nicolas Voituron   +9 more
wiley   +1 more source

Neural Network-Enabled Identification of Weak Inspiratory Efforts during Pressure Support Ventilation Using Ventilator Waveforms. [PDF]

J Pers Med, 2023
Soundoulounaki S, Sylligardos E, Akoumianaki E, Sigalas M, Kondili E, Georgopoulos D, Trahanias P, Vaporidi K.   +7 more
europepmc   +1 more source

Genome‐wide network analysis identifies the lncRNA‐92467/miR‐205‐5p/PTPRM/CAMs axis in a rat model of hypoxic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen, Yi‐Bing Chen, Xin Li, Xiang Xu, Ge Guo, Han‐Lu Li, Yong‐Ming Yao, Chun‐Lei Liu   +7 more
wiley   +1 more source