Results 41 to 50 of about 170,862 (299)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Domiciliary nasal respiratory support : first experiences in Malta [PDF]

, 1997
Nasal respiratory support is a non-invasive alternative to conventional assisted ventilation with endotracheal intubation, or the more cumbersome negative pressure ventilators.
Camilleri, Robert, Galea Debono, Anthony, Montefort, Stephen   +2 more
core  

Influence of respiratory behavior on ventilation, respiratory work and intrinsic PEEP during noninvasive nasal pressure support ventilation in normal subjects. [PDF]

, 2002
BACKGROUND: In clinical practice, patients have different inspiratory behaviors during noninvasive pressure support ventilation (PSV): some breathe quietly, others actively help PSV by an additional effort, and others even resist the inspiratory pressure
el-Khawand, Charbel, Vanpee, Dominique, Delaunois, Luc, Rousseau, Laurent, Jamart, Jacques   +4 more
core   +1 more source

A 5-year registry of mechanically ventilated patients comprising epidemiology, initial settings, and clinical outcome

Egyptian Journal of Chest Disease and Tuberculosis, 2018
Introduction Our primary aim was to document our interactions with patients subjected to mechanical ventilation (MV) in the Critical Care Department focusing on epidemiological characteristics; the initial modes of ventilation used, and initial settings.
Yasser S Nassar, Mena Magdy, Lamia Hamed, Tarek Algohary   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Topographic distribution of tidal ventilation in acute respiratory distress syndrome: effects of positive end-expiratory pressure and pressure support [PDF]

, 2013
OBJECTIVE:: Acute respiratory distress syndrome is characterized by collapse of gravitationally dependent lung regions that usually diverts tidal ventilation toward nondependent regions.
A. Coppadoro, Patroniti, Nicolo', Pesenti, Antonio, Mauri, Tommaso, G. Bellani, Turella, Marta, Confalonieri, Andrea, Bellani, Giacomo, A. Pesenti, A. Confalonieri, Tagliabue, Paola, P. Tagliabue, T. Mauri, N. Patroniti, G. Citerio, Coppadoro, Andrea, Citerio, Giuseppe, M. Turella   +17 more
core   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Comparative effects of proportional assist and variable pressure support ventilation on lung function and damage in experimental lung injury* [PDF]

, 2012
To investigate the effects of proportional assist ventilation, variable pressure support, and conventional pressure support ventilation on lung function and damage in experimental acute lung injury. DESIGN: : Randomized experimental study.
Carvalho, N, Nowack, T, Pelosi, P, Spieth, PM, Beda, A, Güldner, A, Suchantke, S, Engelhard, K, Thal, SC, Kasper, M, de Abreu, MG, Koch, T, Krause, A, Rentzsch, I   +13 more
core   +1 more source

Non-invasive ventilation for acute respiratory failure: pressure support ventilation vs. pressure-controlled ventilation [PDF]

, 2020
Background: The best ventilator mode for patients receiving non-invasive ventilation (NIV) has not been clarified. This study compared the effectiveness of two pressure-targeted modes, i.e., pressure support ventilation (PSV) and pressure-controlled ...
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core   +1 more source