Results 51 to 60 of about 170,862 (299)

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Perfusion of the interventricular septum during ventilation with positive end-expiratory pressure (PEEP) [PDF]

, 1991
Objective: To determine whether regional hypoperfusion of the interventricular septum occurs during ventilation with positive end-expiratory pressure. Design: Animal study. Animals: Anesthetized, closed chest dogs (n = 8).
Schosser, Rudolf, Messmer, Konrad, Schwickert, Christiane, Zwißler, Bernhard, Spengler, Peter, Weiss, Michaela, Iber, Volker   +6 more
core  

Patient-ventilator interaction and sleep in mechanically ventilated patients: Pressure support versus proportional assist ventilation [PDF]

, 2007
OBJECTIVES: To understand the role of patient-ventilator asynchrony in the etiology of sleep disruption and determine whether optimizing patient-ventilator interactions by using proportional assist ventilation improves sleep. DESIGN: Randomized crossover
Ferreyra G., Ambrogio C., Bosma K., Ranieri V. M., Pasero D., Braghiroli A., Appendini L., Mascia L., Mirabella L.   +8 more
core   +1 more source

Tracheostomy and mechanical ventilation weaning in children affected by respiratory virus according to a weaning protocol in a pediatric intensive care unit in Argentina: an observational restrospective trial

Italian Journal of Pediatrics, 2011
We describe difficult weaning after prolonged mechanical ventilation in three tracheostomized children affected by respiratory virus infection. Although the spontaneous breathing trials were successful, the patients failed all extubations.
Frydman Judith, Gonzalez Crotti Patricia, Caprotta Gustavo   +2 more
doaj   +1 more source

Pressure support and positive end-expiratory pressure versus T-piece during spontaneous breathing trial in difficult weaning from mechanical ventilation: study protocol for the SBT-ICU study

Trials, 2022
Background Spontaneous breathing trials are performed in critically ill intubated patients in order to assess readiness to be weaned from mechanical ventilation. In patients with difficult weaning (i.e.
Mehdi Mezidi, Hodane Yonis, Louis Chauvelot, William Danjou, François Dhelft, Alwin Bazzani, Mehdi Girard, Laurent Bitker, Jean-Christophe Richard   +8 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Non-invasive ventilation with intelligent volume-assured pressure support versus pressure-controlled ventilation: effects on the respiratory event rate and sleep quality in COPD with chronic hypercapnia [PDF]

, 2017
Georg Nilius,1,2 Nato Katamadze,1,2 Ulrike Domanski,1 Maik Schroeder,1 Karl-Josef Franke1,2 1HELIOS Klinik Hagen-Ambrock, 2Internal Medicine I, Witten/Herdecke University, Witten, Germany Background: COPD patients who develop chronic hypercapnic ...
Domanski U, Schroeder M, Katamadze N, Franke KJ, Nilius G   +4 more
core  

Newer nonconventional modes of mechanical ventilation

Journal of Emergencies, Trauma and Shock, 2014
The conventional modes of ventilation suffer many limitations. Although they are popularly used and are well-understood, often they fail to match the patient-based requirements.
Preet Mohinder Singh, Anuradha Borle, Anjan Trikha   +2 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Static and dynamic transpulmonary driving pressures affect lung and diaphragm injury during pressure-controlled versus pressure-support ventilation in experimental mild lung injury in rats [PDF]

, 2020
Background: Pressure-support ventilation may worsen lung damage due to increased dynamic transpulmonary driving pressure. The authors hypothesized that, at the same tidal volume (VT) and dynamic transpulmonary driving pressure, pressure-support and ...
Santos R. S., Capelozzi V. L., Rocco P. R. M., Silva P. L., Maia L. A., Carvalho A. C. F., Padilha G. A., Fernandes M. V. S., Pinto E. F., Antunes M. A., Pelosi P., De Abreu M. G., De Machado J. A.   +12 more
core   +1 more source