Results 41 to 50 of about 14,747 (270)

Impacts of diffuse pressure complexes complicate conservation and management of benthic marine habitats

Journal of Applied Ecology
Abstract Human activities exert considerable pressures on marine ecosystems, causing widespread habitat loss (direct footprint) and degradation (diffuse pressures).
Elina A. Virtanen, Louise Forsblom, Laura Kaikkonen, Niko Kallio, Samuli Korpinen, Antti Takolander, Tytti Wärri, Markku Viitasalo   +7 more
openaire   +1 more source

The Application of D(A)PSI(W)R(M) Framework to Coral Reef Conservation

, 2023
A total of 379,834 people visited Ras Mohammed National Park in 2020/21, most of whom snorkelled or dived to see the coral reefs. Current management frameworks seem to be insufficient to tackle the increasing visitation, underlining the need for a ...
Rady Tawfik
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Fear and stressing in predator–prey ecology: considering the twin stressors of predators and people on mammals [PDF]

PeerJ, 2020
Predators induce stress in prey and can have beneficial effects in ecosystems, but can also have negative effects on biodiversity if they are overabundant or have been introduced.
Loren L. Fardell, Chris R. Pavey, Christopher R. Dickman   +2 more
doaj   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Trade-Offs in Marine Policy Decisions Through the Lens of Literature

Oceans
The ocean is increasingly affected by the rise in maritime activities. Increased anthropogenic pressures have led to environmental impacts and also intensified competition for space and resources among various socioeconomic sectors.
Joyce Dias Gois Rodrigues de Queiroz, Débora Gutierrez, Helena Maria Gregório Pina Calado   +2 more
doaj   +1 more source

Nested Socio-Ecological Maps as a Spatial Planning Instrument for Estuary Conservation and Ecosystem-Based Management

Frontiers in Marine Science, 2021
Estuaries are socio-ecological systems that can be represented as a holistic combination of biotic and abiotic conditions in spatially explicit units defined by: (i) the ecotope, as the integration of the physiotope (abiotic-homogeneous units) and the ...
Cristina Galván, Araceli Puente, José A. Juanes   +2 more
doaj   +1 more source

Nature conservation and urban development control in the portuguese planning system: a new impetus against old praxis?

, 2008
Natura 2000 areas bring a new incentive to assess the performance of land-use planning in protecting environmental values from the impacts of development pressures.
Fidélis, Teresa, Sumares, David
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source