Results 111 to 120 of about 4,236 (290)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

'An analysis of the ongoing erosion of the presumption of innocence in Irish law’

open access: yes, 2022
This thesis provides a comprehensive overview of the presumption of innocence in Irish law. It argues that the scope of the presumption of innocence is not confined to narrow evidential rules at criminal trials but is a broader right extending beyond the
Mc Namara, Michael
core  

Evidence of Criminal Acts of Origin in The Prevention and Eradication of Money Laundering Law Under Presumption of Innocence Principle

open access: yesAlauddin Law Development Journal
This study aims to determine the contradiction between the provisions on the proof of the original criminal act with the principle of Presumption of Innocence in the Anti-Money Laundering Law 2010.
Fadli Yasser Arafat J.   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Constitutional presumption of innocence and the institution of release from criminal liability: correlation issues

open access: yesКонституційно-правові академічні студії
The purpose of the article is to determine, taking into account the results of the analysis of the current legislation of Ukraine and the provisions of the doctrine of criminal law, the issues of correlation and ensuring the compliance of the ...
Yaroslav Stupnyk, Maryna Stupnyk
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

CONSIDERATIONS ON THE PRINCIPLE OF PRESUMPTION OF INNOCENCE, ITS EVOLUTION IN BRAZILIAN LAW AND THE POSSIBLE IMPUNITY PRINTING IMPOSED BY THE TRIAL HABEAS CORPUS 84.078

open access: yesTravessias, 2013
This research will seek to analyze, through a study of jurisprudence and doctrinal understanding as constitutional by the Supreme Court in the trial of Habeas 84,078, which declared unconstitutional the provisional execution of the sentence and the ...
Bruno Rafael Cipriano, Ricardo Feistler
doaj  

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