Results 121 to 130 of about 56,302 (303)
Conviction of the Innocent; from the Judicial Error to the Real Innocence [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i Kiyfarī, 2014 Wrongful conviction of the innocent is a type of miscarriage of justice. Thus, the perspective that believes these two concepts are equivalent is false. Innocence can be actual or legal. The actual innocent is who does not commit the crime.
Muhammad Farajiha, Jamshid Gholamlou
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Dark side of the plea bargaining [PDF]
Zbornik Radova: Pravni Fakultet u Novom Sadu, 2019 Plea bargaining is a procedural mechanism through which criminal case is resolved without trial, by consensus of the parties. The agreement consists of the defendant pleading guilty in exchange for prosecutor's promise to charge him less serious than is ...
Bajović Vanja M.
doaj
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The rationale for detention in the Jordanian Code of criminal procedure: A comparative study with French law. [PDF]
Heliyon, 2022 Abuanzeh A.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Revista Vasca de Administración Pública, 2017 As a result of the case law by the European Court of Human Rights, the Constitutional Court was compelled to rectify its former doctrine by broadening the scope of the right to the presumption of innocence beyond punitive administrative resolutions and ...
Silvia del Saz Cordero
doaj +1 more source
Wrongful Convictions, Constitutional Remedies, and \u3ci\u3eNelson v. Colorado\u3c/i\u3e [PDF]
, 2018 The end result in Nelson will satisfy nearly everyone’s sense of basic justice, at least insofar as the monetary refund is concerned. Still, the case is interesting not for its outcome but because the Court’s analysis touches on, but fails to fully ...
Wells, Michael L.
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source