Results 121 to 130 of about 167,430,696 (282)

La inútil prolongación de la agonía del artículo 294 de la Ley Orgánica del Poder Judicial (Comentario a las SSTC 8/2017, de 19 de enero, y 10/2017, de 30 de enero)

open access: yesRevista Vasca de Administración Pública, 2017
As a result of the case law by the European Court of Human Rights, the Constitutional Court was compelled to rectify its former doctrine by broadening the scope of the right to the presumption of innocence beyond punitive administrative resolutions and ...
Silvia del Saz Cordero
doaj   +1 more source

Staging colorectal cancer with the TNM 7(th): the presumption of innocence when applying the M category. [PDF]

open access: yesWorld J Gastroenterol, 2013
Puppa G   +5 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Presumptions of Innocence

open access: yes, 2015
First paragraph: An explanation of the Presumption of Innocence (PoI) must tell us what is to be presumed, of whom, by whom, to what effect, and what can defeat that presumption.
Duff, R A
core  

Presumption of innocence in the media

open access: yes, 2021
Bakalaura darba temats ir “Nevainīguma prezumpcija medijos”. Temata izvēle pamatota ar nevainīguma prezumpcijas kā fundamentāla kriminālprocesa principa pastāvēšanu līdztekus mediju telpā atspoguļotajai informācijai, izvirzīti iespējamie ...
Budeviča, Kristīne
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Presumption of innocence in criminal proceedings

open access: yes
The article examines the content and significance of the principle of the presumption of innocence as a fundamental basis of criminal proceedings and a key guarantee for the protection of human rights and freedoms.
A. A. Sorokin, P. R. Preis
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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