Results 121 to 130 of about 58,866 (354)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Evidence of Criminal Acts of Origin in The Prevention and Eradication of Money Laundering Law Under Presumption of Innocence Principle

Alauddin Law Development Journal
This study aims to determine the contradiction between the provisions on the proof of the original criminal act with the principle of Presumption of Innocence in the Anti-Money Laundering Law 2010.
Fadli Yasser Arafat J., Muhammad Fadhlan Fadhil Bahri, Muhammad Arfhani Ichsan A.H., Asrullah   +3 more
doaj   +1 more source

The Challenges of the Presumption of Innocence in Lithuanian Criminal Proceedings

Acta Prosperitatis
Although one of the key principles of the criminal procedure law - the presumption of innocence is officially declared as an aspiration in Lithuanian legal regulation and case law, there are still some areas of possible threat to this key principle ...
Giedrius Nemeikšis
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

PRESUMPTION OF INNOCENCE OF LEGAL PERSONS

Administrative and Criminal Justice, 2016
There is a link between a presumption of innocence and the right to a fair trial. The rights of a legal person, to be regarded as innocent, protection is ensured by the guarantees in law. The Court of Justice has recognized that the right to the presumption of innocence, the legal persons does not apply in the same way as natural persons.
openaire   +2 more sources

THE PRESUMPTION OF INNOCENCE AS A FUNDAMENTAL HUMAN RIGHT IN THE JURISPRUDENCE OF THE EUROPEAN COURT OF HUMAN RIGHTS

Valahia University Law Study
Although intensely claimed, the presumption still has an unclear outline, but which asserts its identity progressively and evolving through the European Court of Human Rights (to abbreviate E.Ct.H.R). jurisprudence.
Alin Petrea
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Constitutional presumption of innocence and the institution of release from criminal liability: correlation issues

Конституційно-правові академічні студії
The purpose of the article is to determine, taking into account the results of the analysis of the current legislation of Ukraine and the provisions of the doctrine of criminal law, the issues of correlation and ensuring the compliance of the ...
Yaroslav Stupnyk, Maryna Stupnyk
doaj   +1 more source

The Presumption of Innocence in International Criminal Law: Selected Issues

Uzhhorod National University Herald. Series: Law
It is noted that the concept of the presumption of innocence is a fundamental element of the modern legal system and a key principle of criminal law.
M. P. Hnatenko
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source