Results 141 to 150 of about 58,278 (391)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Travessias, 2013 This research will seek to analyze, through a study of jurisprudence and doctrinal understanding as constitutional by the Supreme Court in the trial of Habeas 84,078, which declared unconstitutional the provisional execution of the sentence and the ...
Bruno Rafael Cipriano, Ricardo Feistler
doaj
Dark side of the plea bargaining [PDF]
Zbornik Radova: Pravni Fakultet u Novom Sadu, 2019 Plea bargaining is a procedural mechanism through which criminal case is resolved without trial, by consensus of the parties. The agreement consists of the defendant pleading guilty in exchange for prosecutor's promise to charge him less serious than is ...
Bajović Vanja M.
doaj
.Шляхи вирішення деяких проблем на досудовому слідстві. [PDF]
, 2011 Смоков С.М. .Шляхи вирішення деяких проблем на досудовому слідстві. / С.М. Смоков // Актуальні проблеми політики : зб. наук. пр. / редкол. : С. В. Ківалов (голов. ред.), Л. І. Кормич (заст. голов. ред.), Ю. П. Аленін [та ін.] ; МОНмолодьспорт України, НУ
Smokov, S. +2 more
core
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Revista Vasca de Administración Pública, 2017 As a result of the case law by the European Court of Human Rights, the Constitutional Court was compelled to rectify its former doctrine by broadening the scope of the right to the presumption of innocence beyond punitive administrative resolutions and ...
Silvia del Saz Cordero
doaj +1 more source
The Presumption of Innocence between Theory and Practice [PDF]
, 2016 The presumption of innocence remains adjacent to the accused at all stages of the criminal case , and through these stages are not seen as a convicted or the offense is committed ascribed to really and truly , it is treated on the grounds that the ...
Al-Qatawneh, Ibrahim
core +1 more source