Results 71 to 80 of about 56,302 (303)
This chapter examines a postcard which is readily available at the International Criminal Tribunal for the Former Yugoslavia. As an object of international criminal law, the postcard reveals a great deal about the aims of international criminal law, and ...
Rigney, Sophie
core +2 more sources
False Presumptions Counter to the Presumptions of Innocence
American criminal procedure is condemned as ineffective, because delay and technicality intervene on behalf of the accused. The sanction of the law is neither swift nor inexorable. Not only do "the wicked flee where no man pursueth," but the prisoner enmeshed is preserved from punishment by over-sedulous respect for his rights. Mr.
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
One of the basic principles that falls under the right to a fair trial of the European Convention for the Protection of Human Rights and Fundamental Freedoms (the Convention), is the presumption of innocence. Namely, the Article 6 Paragraph 2 prescribes
Katerina Krstevska Savovska
doaj
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
What's in a name? the UK newspapers' fabrication and commodification of Foxy Knoxy [PDF]
This chapter analyses how, immediately after the arrest of Amanda Knox, the UK’s national press played a pivotal role in transforming the American student into ‘Foxy Knoxy’, the duplicitous, psychologically disturbed femme fatale who orchestrated and ...
Goluandris, A., McLaughlin, E.
core +1 more source

