Results 171 to 180 of about 138,891 (323)
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Legends, dogmas, presumptions, and demystifications in antibiotic therapy. [PDF]
Blanes Hernández R +4 more
europepmc +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Everyday challenges to women's presence and authority yield greater burnout and less persistence in a male-dominated profession. [PDF]
Williams MJ +9 more
europepmc +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Social Determinants of Cardiovascular Health in the Irish Traveller at Individual, Interpersonal, Community, and Societal Levels: A Medical Student-Led Discourse During Case-Based Learning. [PDF]
Alhaidari B, Meagher F, Daly MJ.
europepmc +1 more source
A Suggested Role for Rebuttable Presumptions in Antitrust Restraint of Trade Litigation [PDF]
core +1 more source

