Results 221 to 230 of about 102,950 (234)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Constructing criminality: a thematic analysis of national news media reporting on self-managed abortion criminalisation in the United States. [PDF]

open access: yesSex Reprod Health Matters
McMahon HV   +6 more
europepmc   +1 more source

High gain and high efficiency soft switching quadratic boost converter for renewable energy applications. [PDF]

open access: yesSci Rep
Elghabsi F   +8 more
europepmc   +1 more source

Capturing the short-lived excited singlet state in crystals of a TADF silver(I) complex.

open access: yesChem Commun (Camb)
Łaski P   +6 more
europepmc   +1 more source

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