Results 31 to 40 of about 253,680 (299)

Pharmacotherapy in Bronchopulmonary Dysplasia: What Is the Evidence?

Frontiers in Pediatrics, 2022
Bronchopulmonary Dysplasia (BPD) is a multifactorial disease affecting over 35% of extremely preterm infants born each year. Despite the advances made in understanding the pathogenesis of this disease over the last five decades, BPD remains one of the ...
Rishika P. Sakaria, Ramasubbareddy Dhanireddy, Ramasubbareddy Dhanireddy   +2 more
doaj   +1 more source

Progesterone and preterm birth [PDF]

International Journal of Gynecology & Obstetrics, 2020
AbstractProgestogens (vaginal progesterone and intramuscular 17‐hydroxyprogesterone acetate) are widely recommended for women at high risk of preterm birth. Typical regimens include 17‐hydroxyprogesterone caproate (250 mg intramuscularly weekly), starting at 16–20 gestational weeks until 36 weeks or delivery for women with a singleton gestation and a ...
openaire   +5 more sources

Inflammatory Response in Preterm and Very Preterm Newborns with Sepsis [PDF]

Mediators of Inflammation, 2016
The response of the adaptive immune system is usually less intense in premature neonates than term neonates. The primary objective of this study was to determine whether immunological parameters vary between preterm (PT) neonates (≥32 weeks of gestational age) and very preterm (VPT) neonates (<32 weeks of gestational age).
Enrique Segura-Cervantes, Javier Mancilla-Ramírez, Jorge González-Canudas, Erika Alba, René Santillán-Ballesteros, Deneb Morales-Barquet, Gabriela Sandoval-Plata, Norma Galindo-Sevilla   +7 more
openaire   +3 more sources

Ethanol for preventing preterm birth in threatened preterm labor [PDF]

Cochrane Database of Systematic Reviews, 2014
Preterm birth is the leading cause of death and disability in newborns worldwide. A wide variety of tocolytic agents have been utilized to delay birth for women in preterm labor. One of the earliest tocolytics utilized for this purpose was ethanol infusion, although this is not generally used in current practice due to safety concerns for both the ...
Haas, David M., Morgan, Amanda M., Deans, Samantha J., Schubert, Frank P.   +3 more
openaire   +3 more sources

Extremely Preterm Infants Have a Higher Fat Mass Percentage in Comparison to Very Preterm Infants at Term-Equivalent Age

Frontiers in Pediatrics, 2020
Background: Early nutritional support of preterm infants is important because it influences long-term health and development. Body composition has an influence on cardiovascular disease, metabolic syndrome, and neurocognitive outcome in the long term ...
Marlies Bruckner, Zahra Khan, Christoph Binder, Nicholas Morris, Bernadette Windisch, Sandra Holasek, Berndt Urlesberger   +6 more
doaj   +1 more source

Neuroprotection of the preterm brain [PDF]

, 2019
Despite notable advances in the care and survival of preterm infants, a significant proportion of preterm neonates will have life-long cognitive, behavioral, and motor deficits, and robustly effective neuroprotective strategies are still missing. These therapies must target the pathophysiologic mechanisms observed in contemporaneous infants and rely on
Pierre Gressens, Pierre Gressens, Bobbi Fleiss   +2 more
openaire   +6 more sources

Nephrocalcinosis in preterm neonates [PDF]

Pediatric Nephrology, 2010
The prevalence of nephrocalcinosis (NC) in preterm neonates in recent reports is 7-41%. The wide range in prevalence is a consequence of different study populations and ultrasound equipment and criteria, in addition to a moderate interobserver variation.
Albert J. van der Heijden, Eveline A. Schell-Feith, Joana E. Kist-van Holthe   +2 more
openaire   +3 more sources

Preterm pigs for preterm birth research: reasonably feasible

Frontiers in Physiology, 2023
Preterm birth will disrupt the pattern and course of organ development, which may result in morbidity and mortality of newborn infants. Large animal models are crucial resources for developing novel, credible, and effective treatments for preterm infants.
Jing Sun, Jing Sun, Jing Sun, Jie Chong, Jie Chong, Jinwei Zhang, Jinwei Zhang, Jinwei Zhang, Liangpeng Ge, Liangpeng Ge, Liangpeng Ge   +10 more
openaire   +3 more sources

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

Quantitative Preterm EEG Analysis: The Need for Caution in Using Modern Data Science Techniques

Frontiers in Pediatrics, 2019
Hemodynamic changes during neonatal transition increase the vulnerability of the preterm brain to injury. Real-time monitoring of brain function during this period would help identify the immediate impact of these changes on the brain.
John M. O'Toole, Geraldine B. Boylan
doaj   +1 more source