Results 101 to 110 of about 309,065 (289)

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Maternal dyslipidemia and risk for preterm birth.

PLoS ONE, 2018
Maternal lipid profiles during pregnancy are associated with risk for preterm birth. This study investigates the association between maternal dyslipidemia and subsequent preterm birth among pregnant women in the state of California.
Caitlin J Smith, Rebecca J Baer, Scott P Oltman, Patrick J Breheny, Wei Bao, Jennifer G Robinson, John M Dagle, Liang Liang, Sky K Feuer, Christina D Chambers, Laura L Jelliffe-Pawlowski, Kelli K Ryckman   +11 more
doaj   +1 more source

PRETERM BIRTH

, 2022
Annotation Premature birth occurs for various reasons. Most preterm births happen spontaneously. Quality care before and during pregnancy and between pregnancies ensures a positive pregnancy experience for all women.
Pardabaevna, Isroilova Guljannat, Shaxnoza, Berdiqulova   +1 more
openaire   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Evaluation of a two-tier preterm birth prevention service in a tertiary hospital in the United Kingdom: a retrospective cohort study

BMC Pregnancy and Childbirth
Background Preterm birth is the most important cause of neonatal morbidity and mortality. Clinical guidelines recommend assessment of risk of preterm birth and implementation of interventions to reduce preterm birth risk through dedicated preterm birth ...
Michael Shea, Carolina Longo, Valentina LeThanh, Natasja Vandepitte, Joris Hemelaar   +4 more
doaj   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh, Ofek Levi, Nili Stein, Amir Yahav, Naomi Gronich   +4 more
wiley   +1 more source

Revisiting the association between maternal and offspring preterm birth using a sibling design

BMC Pregnancy and Childbirth, 2019
Background Previous studies have reported an intergenerational association between maternal and offspring preterm birth (PTB) but the nature of the association remains unclear.
Marcelo L. Urquia, Elizabeth Wall-Wieler, Chelsea A. Ruth, Xiaoqing Liu, Leslie L. Roos   +4 more
doaj   +1 more source

Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod

Developmental Dynamics, EarlyView.
Abstract Background Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth. Precocial species, which are ambulatory at birth, develop advanced skeletal maturity in utero and experience postnatal development under mechanical loading.
Christopher J. Panebianco, Maha Essaidi, Elijah Barnes, Ashley Williams, Karin Vancíková, Margot C. Labberté, Pieter Brama, Niamh C. Nowlan, Joel D. Boerckel   +8 more
wiley   +1 more source

Women with epilepsy: Evidence‐based counseling across the lifespan

Epilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn, Georgia Ramantani, Dominique Flügel, Verena Gaus, Susanne Schubert‐Bast, Elisabeth Sellitto, Jennifer Bausch, Bettina Schmitz   +7 more
wiley   +1 more source

In vivo characterization of connective tissue remodeling using infrared photoacoustic spectra [PDF]

, 2018
Premature cervical remodeling is a critical precursor of spontaneous preterm birth, and the remodeling process is characterized by an increase in tissue hydration.
Alisio, Mariana, Altieri, Emma, Anderson, Monica, Barber, Sabrina, Burger, Tracy, Chubiz, Jessica, Diveley, Emily, England, Sarah K, Garcia-Uribe, Alejandro, Goldstein, Naomi, Helm, Kristi, Hu, Peng, Kramer, Christine, Li, Chiye, Ma, Jun, Macones, George A, Maslov, Konstantin, Maynard, Jennifer, McCarthy, Ronald, Meyenburg, Kaytelyn, Meyers, Karen, Muench, Lisa, Onwumere, Oji, Pizzella, Stephanie, Punyamurthy, Nina, Qu, Yuan, Shi, Junhui, Slaughter, Janessia, Stout, Molly J, Tuuli, Methodius, Wang, Lihong V, Zhao, Peinan   +31 more
core   +1 more source