Results 71 to 80 of about 5,071,401 (351)

Unreliable estimation of prevalence of fetal alcohol syndrome [PDF]

, 2017
Svetlana Popova and colleagues (March, 2017)1 sought to estimate the global, regional, and national prevalence of alcohol use during pregnancy and fetal alcohol syndrome (FAS).
Busardã², Francesco Paolo, Ceccanti, Mauro, Pacifici, Roberta, Pichini, Simona, Tarani, Luigi   +4 more
core   +3 more sources

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

FEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause, Musalula Sinkala, Raj Ramesar   +2 more
wiley   +1 more source

Mid-term outcomes of percutaneous pulmonary valve replacement with Edwards-Sapien bioprosthesis in native right ventricular outflow tract

Scientific Reports
Information on mid-term outcomes of percutaneous pulmonary valve replacement (PPVR) with the Edwards Sapien (ES) valve in the native right ventricular outflow tract (RVOT) are limited.
Yassin Belahnech, Gerard Martí-Aguasca, Laura Dos-Subirà, Pedro Betrian-Blasco, Bruno García del Blanco, Maria Calvo-Barceló, Eduard Ródenas-Alesina, Antonia Pijuan-Domènech, Ferran Gran, Queralt Ferrer, Gemma Giralt-García, Berta Miranda, Blanca Gordon, Víctor González-Fernández, José A. Barrabés, Ferran Roses-Noguer, Ignacio Ferreira-González   +16 more
doaj   +1 more source

Farmers' practices and factors associated with the prevalence of all lameness and lameness attributed to interdigital dermatitis and footrot in sheep flocks in England in 2004 [PDF]

, 2009
The aim of this study was to investigate whether the risk factors associated with all causes of lameness in sheep differed from those associated with the lesion specific causes of lameness, interdigital dermatitis (ID) and footrot (FR).
Green, Laura E., Kaler, Jasmeet
core   +1 more source

Prevalence of Physical Activity and Sedentary Behavior among Chinese Children and Adolescents: Variations, Gaps, and Recommendations [PDF]

, 2020
Physical-activity (PA) and sedentary-behavior (SB) assessment is of particular importance in the promotion of health in young people. However, there is no comprehensive overview of PA and SB from national surveys among Chinese children and adolescents ...
Chen, Si-Tong, Clark, Cain, Hong , Jin-Tao, Liu , Yang, Shen , Hejun, Yan, Jin, Yang , Xian-Nan   +6 more
core   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Incorporating survival data into case-control studies with incident and prevalent cases [PDF]

arXiv, 2020
Typically, case-control studies to estimate odds-ratios associating risk factors with disease incidence from logistic regression only include cases with newly diagnosed disease. Recently proposed methods allow incorporating information on prevalent cases, individuals who survived from disease diagnosis to sampling, into cross-sectionally sampled case ...
arxiv  

Combination interventions to prevent HCV transmission among people who inject drugs: modelling the impact of antiviral treatment, needle and syringe programs, and opiate substitution therapy [PDF]

, 2013
BackgroundInterventions such as opiate substitution therapy (OST) and high-coverage needle and syringe programs (HCNSP) cannot substantially reduce hepatitis C virus (HCV) prevalence among people who inject drugs (PWID).
Aspinall, Bukten, Cornish, David J. Goldberg, De Angelis, Degenhardt, Dore, Durier, Gane, Grebely, Guinness, Hellard, Hickman, Liu, Lozano, Macarthur, Martin, Martin, Martin, Martin, Matthew Hickman, Micallef, Natasha K. Martin, Nelson, Nordt, Peter Vickerman, Poordad, Sharon J. Hutchinson, Shepard, Sweeting, Turner, Vickerman, Vickerman   +32 more
core   +3 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source