Results 91 to 100 of about 4,121,422 (285)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Impact of the Noninvasive Diagnostic Algorithm on Clinical Presentation and Prognosis in Cardiac Amyloidosis

JACC: Advances
Background: The introduction of a noninvasive diagnostic algorithm in 2016 led to increased awareness and recognition of cardiac amyloidosis (CA). Objectives: The purpose of this study was to analyze the impact of the introduction of the noninvasive ...
Giacomo Tini, MD, Ernesto Cristiano, MD, Mattia Zampieri, MD, Alberto Ponziani, MD, Aldostefano Porcari, MD, Margherita Zanoletti, MD, Carlotta Mazzoni, MD, Matteo Sclafani, MD, Giulia Saturi, MD, Andrea Lalario, MD, Marianna Eleonora Labate, MD, Camillo Autore, MD, Emanuele Barbato, MD, Federico Perfetto, MD, Elena Biagini, MD, Gianfranco Sinagra, MD, Marco Canepa, MD, Marco Merlo, MD, Simone Longhi, MD, Francesco Cappelli, MD, Beatrice Musumeci, MD   +20 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Worldwide distribution of human papillomavirus types in cytologically normal women in the International Agency for Research on Cancer HPV prevalence surveys: a pooled analysis

, 2005
Background The proportion of women infected with human papillomavirus (HPV) varies greatly across populations, as might the distribution of HPV types.
Molano, M, Shin, HR, S de Sanjosé, Tunsakul, S, GM Clifford, Sukvirach, S, JO Thomas, PJF Snijders, PTH Anh, Meijer, CJLM, Matos, E, Gallus, S, Ronco, G, E Matos, Thomas, JO, S Tunsakul, Ferreccio, C, HR Shin, C Ferreccio, Snijders, PJF, CJLM Meijer, N Muñoz, Vaccarella, S, S Vaccarella, S Franceschi, NT Hieu, R Rajkumar, Munoz, N, Herrero, R, M Molano, S Sukvirach, Rajkumar, R, G Ronco, Franceschi, S, Hieu, NT, R Herrero, Anh, PTH, Clifford, GM, de Sanjose, S, S Gallus   +39 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Venous congestion in a d-TGA patient after Mustard procedure

REC: Interventional Cardiology (English Ed.)
A 45-year-old patient with dextro-transposition of the great arteries (d-TGA) repaired via Mustard procedure at the age of 5 years presented with lower limb venous congestion.
Francisco Javier Ruperti-Repilado, Félix Coserria-Sánchez, Amadeo Wals-Rodríguez, Agustín Guisado, José Díaz-Fernández, Pastora Gallego   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Congestión venosa en paciente con d-TGA tras Mustard

REC: Interventional Cardiology
Este es el caso de un varón de 45 años con dextrotransposición de las grandes arterias (d-TGA) reparada mediante la operación de Mustard a la edad de 5 años con un cuadro de congestión venosa en las extremidades ...
Francisco Javier Ruperti-Repilado, Félix Coserria-Sánchez, Amadeo Wals-Rodríguez, Agustín Guisado, José Díaz-Fernández, Pastora Gallego   +5 more
doaj   +1 more source

Physical Restraints in Geriatric Care in Sweden: Prevalence and Patient Characteristics

, 1996
OBJECTIVE: Physical restraints are used frequently in geriatric care to promote the safety of frail older patients. This study investigated the prevalence of the use of physical restraints in geriatric care and the way in which patient characteristics ...
Bucht, Gosta, Karlsson, Stig, Eriksson, Sture, Sandman, P.O.   +3 more
core   +1 more source

Ecological study of socio-economic indicators and prevalence of asthma in schoolchildren in urban Brazil. [PDF]

, 2007
BACKGROUND: There is evidence of higher prevalence of asthma in populations of lower socio-economic status in affluent societies, and the prevalence of asthma is also very high in some Latin American countries, where societies are characterized by a ...
Genser Bernd, Bernd Genser, Pujades-Rodriguez, Mar, Barreto, Mauricio Lima, da Cunha, Sérgio Souza, Sérgio Souza da Cunha, Mauricio Lima Barreto, Rodrigues, LC, Rodrigues Laura C, Pujades-Rodriguez Mar, Mar Pujades-Rodriguez, Laura C Rodrigues, Genser, Bernd, Barreto, ML, da Cunha, SS, Rodrigues, Laura C, da Cunha Sérgio, Barreto Mauricio, Pujades-Rodriguez, M, Genser, B   +19 more
core   +2 more sources