Results 171 to 180 of about 7,991,089 (298)

Nearly Two Decades of Sustaining a Coalition to Prevent Youth Substance Use: Reflections From the Genesee County Prevention Coalition, Michigan. [PDF]

J Public Health Manag Pract
Fockler L, Koffkey C, Baranek B, Wright-Kelly E.   +3 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

AI-powered retinal imaging for early ASCVD risk stratification in a hybrid care model: preliminary findings from SAFER. [PDF]

Front Artif Intell
Zakaria H, Ali J, Ibrahim MG, Roman I, Hashemi A, Almarzooqi I.   +5 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Vitamin D3 and calcium to prevent hip fractures in elderly women.

New England Journal of Medicine, 1992
M. Chapuy, M. Arlot, F. Duboeuf, J. Brun, Bridgette Crouzet, S. Arnaud, P. Delmas, P. Meunier   +7 more
semanticscholar   +1 more source

What's good for the heart is good for the brain? Evidence from a rural cohort on the longitudinal relationship between atherosclerotic cardiovascular disease risk and cognitive decline. [PDF]

J Prev Alzheimers Dis
Ulep MG.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A multicomponent intervention to prevent delirium in hospitalized older patients.

New England Journal of Medicine, 1999
S. Inouye, S. Bogardus, Peter A. Charpentier, L. Leo-Summers, D. Acampora, T. Holford, L. M. Cooney   +6 more
semanticscholar   +1 more source

Genetic and molecular evidence linking CTSH to Alzheimer's disease pathophysiology. [PDF]

Alzheimers Dement
Picard C, Aumont-Rodrigue G, Sarty I, Loncke J, Savard M, Maligne-Bruneau L, Poirier J, PREVENT‐AD research group.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source