Results 101 to 110 of about 8,076,451 (351)
Risk related to household pets in contact with Ebola cases in humans
EFSA Journal, 2014 In response to a request from the European Commission to provide advice on risks related to pets having been in contact with people infected with Ebola virus, EFSA and ECDC have jointly prepared a rapid assessment.
European Food Safety Authority +1 more
doaj +1 more source
Proven HIV Prevention Strategies [PDF]
Describes strategies that, used in combination, have proven to be effective in preventing sexual, blood-borne, and mother-to-child transmission of HIV.
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Comparing Strategies to Prevent Stroke and Ischemic Heart Disease in the Tunisian Population: Markov Modeling Approach Using a Comprehensive Sensitivity Analysis Algorithm. [PDF]
Background. Mathematical models offer the potential to analyze and compare the effectiveness of very different interventions to prevent future cardiovascular disease.
Bandosz, P +8 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
EFSA JournalThis report presents the main findings of the 2022–2023 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans and food‐producing animals (broilers, laying hens and fattening ...
European Food Safety Authority +1 more
doaj +1 more source
EFSA Journal, 2011 The European Food Safety Authority and the European Centre for Disease Prevention and Control have analysed the information on antimicrobial resistance among zoonotic and indicator bacteria in 2009 submitted by 25 European Union Member States.
European Food Safety Authority +1 more
doaj +1 more source
Investing in America's Health: A State-By-State Look at Public Health Funding and Key Health Facts 2011 [PDF]
Examines state trends, variations, and rankings in key health indicators and federal, state, and local funding for public health programs.
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