Results 121 to 130 of about 8,076,451 (351)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1612-1625, June 2026.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Poised for Prevention: Advancing Promising Approaches to Primary Prevention of Intimate Partner Violence [PDF]

open access: yes
Includes a discussion of primary prevention of partner violence, promising approaches to environmental/norms change, an examination of primary prevention within immigrant communities, and recommended actions and immediate next ...
Larry Cohen   +2 more
core  

Low level of attention to health inequalities in prevention planning activities of the Italian Regions [PDF]

open access: yes
Background: Health promotion and prevention activities should tackle health inequalities to reduce disparities in health among disadvantaged populations.
D'ANDREA, ELVIRA   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

500 Cities Project: Local Data for Better Health 2014 [PDF]

open access: yes
The 500 Cities Project-Local Data for Better Health-is a collaboration among the Robert Wood Johnson Foundation, the CDC Foundation, and the Centers for Disease Control and Prevention (CDC), whose purpose is to provide high quality small area estimates ...
Center for Disease Control and Prevention   +1 more
core  

If Preventable Why Not Prevented? [PDF]

open access: yesJournal of the Royal Society of Medicine, 1988
openaire   +2 more sources

The Prevention of Dementia

open access: yesEuropean Journal of Cardiovascular Prevention & Rehabilitation, 2001
AbstractObjectiveDementia is prevalent in older adults and the population is ageing. Many factors have been associated with dementia and anything that may aid the prevention of dementia is of importance.MethodThe literature in this area was evaluated and information relating to the various factors that may impact upon the prevention of dementia is ...
openaire   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Nosocomial Infection Prevention Through Universal Precaution in YOGYAKARTA Muhammadiyah Hospital [PDF]

open access: yes
Prevention of nosocomial infections in hospitals can be done through the implementation of universal precaution program or action asepsis and antisepsis tapping. These actions undertaken by health workers, both nurses and physicians, universal precaution
Handayani, L. (Lina)   +4 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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