Results 141 to 150 of about 8,076,451 (351)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Sensitive Coverage Saves Lives: Improving media portrayal of suicidal behaviour [PDF]

open access: yes
The report outlines the results of consultations with journalists, suicide prevention agencies and mental health groups conducted by the journalism ethics charity MediaWise.
Cookson, R.   +5 more
core  

Primary prevention of ischaemic cardiovascular disorders with antiplatelet agents.

open access: yes
In those who have already survived myocardial infarction (MI) or stroke, or have had a transient ischaemic episode (TIA), daily low dose aspirin (ASA) reduces the risk of recurrences by an amount that greatly exceeds the risk of serious bleeding ...
Meade, Tom
core   +1 more source

Preventive Medicine or Disease Prevention [PDF]

open access: yesJournal of the Royal Society of Medicine, 1987
T P Eddy, J S McCormick, G C Cook
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The blueprint for rabies prevention and control: a novel operational toolkit for rabies elimination.

open access: yesPLoS Neglected Tropical Diseases, 2012
Tiziana Lembo   +1 more
doaj   +1 more source

UFO Presents! A viral hepatitis prevention and education program for young adult IDUs [PDF]

open access: yes
UFO Presents! is a Center for Disease Control and Prevention (CDC)-funded program providing much needed hepatitis education, prevention and care services for youth and young adults with injection risk in San Francisco, CA.

core  

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2007
K. Rabe   +10 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Partners in Prevention: Community-Wide Homelessness Prevention in Massachusetts and the United States [PDF]

open access: yes
Examines six community initiatives to prevent homelessness involving cross-organizational resource-sharing, policies, and interventions. Looks at each program's strategy, organization, interventions, and approaches to partnerships, outcomes, and ...
Amy Carlin   +5 more
core  

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