Results 161 to 170 of about 8,076,451 (351)

Katie Edwards, Assistant Professor of Psychology, COLA travels to South Africa and Kenya [PDF]

Prof. Edwards travelled to Africa to learn more about the innovative sexual violence prevention work happening across the African continent and to discuss similarities and differences in violence prevention in South Africa and the U ...
Edwards, Katie M, Ph.D.
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

HIV Prevention in the Era of Expanded Treatment Access [PDF]

Makes recommendations on how to forge a comprehensive response to the global AIDS epidemic by integrating prevention interventions into expanding treatment programs, and on new approaches to prevention that will be required as treatment access ...

core  

Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.

Stroke, 2014
W. Kernan, B. Ovbiagele, Vice Chair, Henry R. Black, Dawn M. Bravata, M. Chimowitz, M. D. Ezekowitz, M. C. Fang, M. Fisher, K. Furie, D. Heck, S. Claiborne, C. Johnston, S. Kasner, S. Kittner, Pamela H. Mitchell, Michael W Rich, D. Richardson, L. H. Schwamm, John A. Wilson   +19 more
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The brain health bundle: integrating evidence-based strategies to guide neurological prevention. [PDF]

Neurol Res Pract
Schaeffer E, Berg D.
europepmc   +1 more source

Evaluation of crime prevention initiatives [PDF]

This third toolbox in the series published by the EUCPN Secretariat focuses on the main theme of the Irish Presidency, which is the evaluation of crime prevention initiatives.
Klima, Noel, O'Duill, Barra, Vanhauwaert, Rosita, Wijckmans, Belinda   +3 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Key aspects to consider in the design of prevention efforts for obsessive-compulsive disorder. [PDF]

World Psychiatry
Mataix-Cols D, Aspvall K, Leckman JF.
europepmc   +1 more source