Results 171 to 180 of about 8,076,451 (351)

Global HIV Prevention: The Access, Funding, and Leadership Gaps [PDF]

open access: yes
Outlines the limited access to HIV prevention services in middle- to low-income countries, insufficient funding to scale-up effective programs, and the lack of global and national leadership on prevention that impedes broader delivery of proven ...

core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Prevention of Catastrophic Volcanic Eruptions [PDF]

open access: yes
Giant volcanic eruptions emit sulphate aerosols as well as volcanic ash. Needless to say that volcanic ash causes significant damage to the environment and human at large. However, the aerosols are even worse.
Dassanayake, Abn   +3 more
core  

Ocular traumatology: prevention, prevention, prevention... [PDF]

open access: yesGraefe's Archive for Clinical and Experimental Ophthalmology, 2010
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Proteomic responses to the effect of coprophagy prevention on meat quality in New Zealand white rabbits. [PDF]

open access: yesFood Chem (Oxf)
He H   +9 more
europepmc   +1 more source

Statins for primary and secondary prevention in the oldest old : an overview of the existing evidence [PDF]

open access: yes
Hypercholesterolemia, although a modifiable risk factor for cardiovascular disease, is still one of the leading causes of death among older people in western countries.
Petrovic, Mirko   +2 more
core  

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