Results 191 to 200 of about 8,076,451 (351)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Suicide Prevention [PDF]

Australasian Journal on Ageing, 1998
openaire   +2 more sources

Primary prevention of cardiovascular disease with a Mediterranean diet.

New England Journal of Medicine, 2013
R. Estruch, E. Ros, J. Salas‐Salvadó, M. Covas, D. Corella, F. Arós, E. Gómez-Gracia, V. Ruíz-Gutiérrez, M. Fiol, J. Lapetra, R. Lamuela-Raventós, L. Serra-Majem, X. Pintó, J. Basora, M. Muñoz, J. Sorlí, J. A. Martínez, M. Martínez-González   +17 more
semanticscholar   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Role of allied health professions in falls prevention for community-dwelling older adults: a scoping review. [PDF]

BMJ Open
Lawton A, Tripodi N, Wospil R, Wright BM, Menz HB, Martin S, Bonanno DR, Linton C, Bastani A, Ross A, Thomas R, Corcoran D, McNamara T, Baxter D, Vaughan B, Lane R, Feehan J.   +16 more
europepmc   +1 more source

Falls in older people: epidemiology, risk factors and strategies for prevention.

Age and Ageing, 2006
L. Rubenstein
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Eliminating Syphilis fromth e United States

DST, 1999
NationaJ Center of HIV, STD, and TB Prevention Center for Diseas e Control and Prevention , Atlanta - USA
doaj  

Associations of cigarette card games engagement with smoking susceptibility and smoking behaviors among Chinese children and adolescents: Findings from the Zhejiang Childhood Behavior and Health Cohort study. [PDF]

Tob Induc Dis
Yu LH, Lu XQ, Yang XJ, Yu Z, Jiang W, Pan YS, Yang LP, Hu J, Guan YQ, Xu CX, Yao WY, Wang LX, Zhong JM, Wang M.   +13 more
europepmc   +1 more source