Results 81 to 90 of about 2,016,502 (239)

Optimal Control of Prevention and Treatment in a Basic Macroeconomic-Epidemiological Model [PDF]

arXiv, 2019
We analyze the optimal control of disease prevention and treatment in a basic SIS model. We develop a simple macroeconomic setup in which the social planner determines how to optimally intervene, through income taxation, in order to minimize the social cost, inclusive of infection and economic costs, of the spread of an epidemic disease.
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

The European Union summary report on trends and sources of zoonoses, zoonotic agents and food‐borne outbreaks in 2015

EFSA Journal, 2016
This report of EFSA and the European Centre for Disease Prevention and Control presents the results of the zoonoses monitoring activities carried out in 2015 in 32 European countries (28 Member States (MS) and four non‐MS).
European Food Safety Authority, European Centre for Disease Prevention and Control   +1 more
doaj   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

A method for assessing the success and failure of community-level interventions in the presence of network diffusion, social reinforcement, and related social effects [PDF]

arXiv, 2018
Prevention and intervention work done within community settings often face unique analytic challenges for rigorous evaluations. Since community prevention work (often geographically isolated) cannot be controlled in the same way other prevention programs and these communities have an increased level of interpersonal interactions, rigorous evaluations ...
arxiv  

Risk related to household pets in contact with Ebola cases in humans

EFSA Journal, 2014
In response to a request from the European Commission to provide advice on risks related to pets having been in contact with people infected with Ebola virus, EFSA and ECDC have jointly prepared a rapid assessment.
European Food Safety Authority, European Centre for Disease Prevention and Control   +1 more
doaj   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

How to prevent type-flaw attacks on security protocols under algebraic properties [PDF]

arXiv, 2010
Type-flaw attacks upon security protocols wherein agents are led to misinterpret message types have been reported frequently in the literature. Preventing them is crucial for protocol security and verification. Heather et al. proved that tagging every message field with it's type prevents all type-flaw attacks under a free message algebra and perfect ...
arxiv  

European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from animals and food in the European Union in 2009

EFSA Journal, 2011
The European Food Safety Authority and the European Centre for Disease Prevention and Control have analysed the information on antimicrobial resistance among zoonotic and indicator bacteria in 2009 submitted by 25 European Union Member States.
European Food Safety Authority, European Centre for Disease Prevention and Control (ECDC)   +1 more
doaj   +1 more source