Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Treatment Strategy for Dyslipidemia in Cardiovascular Disease Prevention: Focus on Old and New Drugs. [PDF]
Pharmacy (Basel), 2018 Zodda D, Giammona R, Schifilliti S.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
CDC\u2019s suicide prevention resource for action
Preventing Suicide is a PriorityCDC\u2019s Suicide Prevention Resource for Action (Prevention Resource) details the strategies with the best available evidence to reduce suicide.
core
Compendium of HIV prevention interventions with evidence of effectiveness : from CDC's HIV/AIDS Prevention Research Synthesis Project [PDF]
Centers for Disease Control and Prevention, HIV/AIDS Prevention Research Synthesis Project. Compendium of HIV Prevention Interventions with Evidence of Effectiveness.
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Phytochemicals from Purwoceng (<i>Pimpinella pruatjan</i>) and Their Potential in Chronic Disease Prevention: Focus on Kidney Health. [PDF]
Int J Mol SciDewi TU +7 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Maintaining prevention focus: the impact of an interdisciplinary taskforce on CAUTI rates during an EMR transition. [PDF]
Antimicrob Steward Healthc EpidemiolPryor R +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Promotion focus, but not prevention focus of teachers and students matters when shifting towards technology-based instruction in schools. [PDF]
Sci RepHoch E, Scheiter K, Sassenberg K.
europepmc +1 more source