Results 181 to 190 of about 461,645 (274)

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Imported malaria: a silent and forgotten threat in malaria free zones? [PDF]

Malar J
Lusiyana N, Ahmad RA, Elyazar I, Murhandarwati EEH.   +3 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Establishment and Validation of a Competency-Based Evaluation Indicator System for On-Site Disinfection Service Providers - Shanghai Municipality, China, 2023. [PDF]

China CDC Wkly
Ji X, Jiang N, Huang L, Fan J, Shi T, Zhang X, Zhu R, Chen J, Wu H, Ban H, Tian L.   +10 more
europepmc   +1 more source

The Boston University Pre-Law Review Volume XXIV Issue 1, Fall 2014 [PDF]

, 2014
Adeosun, Lola, Amatuzzi, Ana Paula, Bailey, Evan, Boots, Aleksandra, Bourne, Jennifer, Broe, Patricia, Cavena, Bill, Chinni, Manasa, Dolci, Paige, Downs, Carolyn, Fikar, Hannah, Finnegan, Cassandra, Gartsbeyn, Cheryl, Goldberg, Natalie, Harper, Catherine, Keuler, Andrew, Knox, Ryan, LeCates, Victoria, Marcus, Alexandra, Mazzarelli, India, Narula, Neha, Park, Jung Hyun, Patel, Disha, Peluso, Katherine, Pico, Merissa, Pollack, Yvette, Ramesh, Shreya, Rollins, Daniel, Silverman, Elizabeth, St. Laurent, Benjamin, Sy, Stella, Viroja, Janki, Willis, Catherine, Yim, Martin   +33 more
core   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Bhutan's Response Against Increasing Number of Stroke (BRAINS): A Hybrid Type II Effectiveness-Implementation Study. [PDF]

Cureus
Yangchen, Pandian JD, Tenzin T, Shao R, Dhakal GP, Rai NB, Yangzom S, Tshering K, Sebastian IA, Gandhi D, Dorji G, Wangchuk T, Tenzin K.   +12 more
europepmc   +1 more source

International environmental law in the Asia-Pacific region: Recent developments [PDF]

, 1989
Mushkat, R
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source