Results 121 to 130 of about 782,060 (307)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Jurnal Ilmiah SINERGIMaintenance planning is the first step in an industry, especially when it comes to the trade-off between cost and reliability, which is the reason for this research's aim. The Reliability Centered Maintenance (RCM) method will be used in this research to
Sally Cahyati +4 more
doaj +1 more source
Terror Financing, Guilt by Association and the Paradigm of Prevention in the ‘War on Terror’ [PDF]
, 2008 Material support has become the watchword of the post-9/11 era. Material support to groups that have been designated as terrorist has been the U.S. government\u27s favorite charge in post-9/11 terrorism prosecutions.
Cole, David
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Analysis of Required Investigations of Work-Related Musculoskeletal Disorders in Spain [PDF]
, 2019 Musculoskeletal disorders (MSD) are the most common source of occupational health problems in Western countries. In Spain, musculoskeletal disorders (MSDs) can be reported either as accidents or occupational diseases.
Carrillo-Castrillo, Jesús Antonio +3 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Realizing Health Reform's Potential: How the Affordable Care Act Will Strengthen Primary Care and Benefit Patients, Providers, and Payers [PDF]
, 2011 Examines issues in primary care and outlines the 2010 healthcare reform law's provisions to strengthen it, including temporary hikes in Medicare and Medicaid payments and support for innovations in care delivery and primary care workforce ...
Georgette Lawlor +3 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Promoting Men's Health: Addressing Barriers to Healthy Lifestyle and Preventive Health Care [PDF]
, 2004 The workshop upon which this report is based drew prominent behavioral and social researchers in men's health and related fields together to develop a consensus about men's health care needs and the ways society and our culture create barriers to the ...
Brigid McHugh +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source