Results 141 to 150 of about 1,618,312 (332)

BUMC Annual Report [PDF]

open access: yes, 1962
Annual report of the Boston University Medical ...
Bakst, Henry J.   +9 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Professional Development for Conservators in the United States: Report of the Directors' Retreat for the Advancement of Conservation Education [PDF]

open access: yes, 2002
Provides a compendium of ideas and suggestions that aim to better define and effectively advance the profession of ...

core  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Plans de sauvegarde et monuments nationaux : réflexion sur les priorités de conservation à propos des collections de moulages

open access: yesIn Situ, 2016
The collections of plaster casts of the architectural decor of nine monuments belonging to the Centre des monuments nationaux were studied in 2013 and 2014. The aim was to envisage their preservation and interpretation.
Geneviève Rager
doaj   +1 more source

DIGITAL TWIN: A HBIM-BASED METHODOLOGY TO SUPPORT PREVENTIVE CONSERVATION OF HISTORIC ASSETS THROUGH HERITAGE SIGNIFICANCE AWARENESS

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
. During preliminary phases of conservation projects, a considerable amount of heterogeneous datasets are produced, gathered, analysed and interpreted.
P. Jouan, P. Hallot
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Air pollutant levels in air-conditioned and naturally ventilated museums: a pilot study [PDF]

open access: yes, 1999
An air-conditioned and a naturally ventilated museum in a highly polluted part of London were compared for effectiveness of pollution control. Nitrogen dioxide, sulphur dioxide and hydrogen sulphide concentrations were measured inside and outside using ...
Blades, N, Cassar, M, Oreszczyn, T
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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