Results 121 to 130 of about 1,886,210 (293)

From Mašrabiya to Ṣaḥn: Managing Indoor Environmental Quality in Cairo’s Islamic Architectural Heritage Under Climatic Pressures

Heritage
Cairo’s Islamic architectural heritage represents one of the world’s most significant concentrations of pre-industrial environmental ingenuity. For over a millennium, an integrated suite of passive climate-control systems—the Mašrabiya latticework screen,
Thowayeb H. Hassan, Mahmoud I. Saleh, Amany E. Salem, Luminita Anca Deac, Jermien Hussein Abd El Kafy, Ahmed Tawhid Eissa   +5 more
doaj   +1 more source

Real-Time Wood Behaviour: The Use of Strain Gauges for Preventive Conservation Applications. [PDF]

Sensors (Basel), 2020
Anaf W, Cabal A, Robbe M, Schalm O.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Health Risk Assessment in the Mass Recovery of Flood-Damaged Archival and Library Collections

Heritage
Flood events have increased significantly in recent decades as a result of climate change, causing severe damage to cultural heritage and, in particular, to archival and library collections.
Matteo Montanari, Roberta Taddei, Lia Bardasi, Pietro Livi, Donatella Matè, Maria Carla Sclocchi   +5 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Publication : EPICO - European Protocol In Preventive Conservation, phase 1

, 2017
EPICO - European Protocol In Preventive Conservation, phase 1 Ouvrage publié avec le soutien scientifique du CRCV dans le cadre du programme de recherche appliquée du Centre « EPICO - La conservation préventive dans les demeures historiques et les ...
CRCV
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Integrating Hydroxyapatite-Based Material Innovation Into Digital Heritage Systems: A Data-Driven Framework for Sustainable Heritage Conservation

Scientific Bulletin of Valahia University: Materials and Mechanics
Cultural heritage conservation is increasingly affected by environmental degradation, climate change, and intensified human pressures, which accelerate the decay of historic materials and call for more resilient and adaptive conservation approaches.
Moşiu Alina, Onescu Iasmina, Ion Rodica-Mariana   +2 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source