Results 101 to 110 of about 125,549 (303)

Análisis fisicoquímico de materiales de embalaje utilizados para almacenar documentos históricos/patrimoniales en instituciones culturales públicas de Costa Rica

open access: yesInformación, Cultura y Sociedad
Para determinar la aptitud de materiales de embalaje elaborados en papel/cartón y empleados en diferentes instituciones públicas a cargo de patrimonio documental costarricense, se llevó a cabo la medición de la acidez (pH) de los materiales, así como el ...
Sharon Ugalde Soto   +2 more
doaj   +1 more source

Urban Containment Policies and Physical Activity A Time–Series Analysis of Metropolitan Areas, 1990–2002 [PDF]

open access: yes, 2008
Background: Urban containment policies attempt to manage the location, character, and timing of growth to support a variety of goals such as compact development, preservation of greenspace, and efficient use of infrastructure.
Aytur, Semra   +3 more
core   +2 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Glass Crystal Models: A First Approach to a Hidden Treasure of Teaching and Scientific Heritage

open access: yesHeritage, 2019
Glass crystal models arrived in Portugal around the late 19th century, when high schools, universities, and polytechnics were gradually provided with teaching collections to support science education. Therefore, they are an important material evidence of
Carolina Peixe   +3 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

PREVENTIVE CONSERVATION [PDF]

open access: yes, 2012
DE NUNTIIS, P, PALLA, Franco, PONTI, F.
openaire   +3 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Plans de sauvegarde et monuments nationaux : réflexion sur les priorités de conservation à propos des collections de moulages

open access: yesIn Situ, 2016
The collections of plaster casts of the architectural decor of nine monuments belonging to the Centre des monuments nationaux were studied in 2013 and 2014. The aim was to envisage their preservation and interpretation.
Geneviève Rager
doaj   +1 more source

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